Senial sinus aspirate samples during high-dose, short-course levofloxacin treatment of acute maxillary sinusitis

被引:10
作者
Anon, Jack B.
Paglia, Margaret
Xiang, Jim
Ambrose, Paul G.
Jones, Ronald N.
Kahn, James B. [1 ]
机构
[1] PriCara, Med Affairs, Unit Ortho McNeil Inc, Raritan, NJ 08869 USA
[2] Univ Pittsburgh, Dept Otolaryngol, Coll Med, Erie, PA 16508 USA
[3] Ortho McNeil Janssen Sci Affairs, Clin Project Management, LLC, Raritan, NJ 08869 USA
[4] Ortho McNeil Janssen Sci Affairs, Quantitat Methodol, LLC, Raritan, NJ 08869 USA
[5] Cognigen Corp, Dept Clin Pharmacol, Buffalo, NY 14221 USA
[6] JMI Labs, N Liberty, IA 52317 USA
关键词
levofloxacin; maxillary sinusitis; sinus aspirate;
D O I
10.1016/j.diagmicrobio.2006.10.019
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
This study assessed daily aspirate samples from an indwelling sinus catheter during high-dose, short-course levofloxacin (750 mg daily x 5 days) treatment of acute maxillary sinusitis. Pathogens were isolated from 4 of 18 recruited patients. Bacteriologic eradication occurred within 24 h for 3 patients and 72 h for the 4th. (c) 2007 Elsevier Inc. All rights reserved.
引用
收藏
页码:105 / 107
页数:3
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