How good is the management of vascular risk after stroke, transient ischaemic attack or carotid endarterectomy?

被引:28
作者
Johnson, Paul [1 ]
Rosewell, Mary [1 ]
James, Martin A. [1 ]
机构
[1] Royal Devon & Exeter Hosp, Dept Med, Exeter EX2 5DW, Devon, England
关键词
transient ischaemic attack; stroke secondary prevention; carotid endarterectomy; blood pressure; hyperlipidaemia;
D O I
10.1159/000097053
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background: Patients remain at high risk of vascular events after stroke, transient ischaemic attack or carotid endarterectomy. We studied how well this risk is addressed by the effective treatment of modifiable risk factors. Methods: A total of 198 consecutive attenders at a rapid access stroke clinic and 98 consecutive patients undergoing carotid endarterectomy were studied. Treatment of hypertension and hyperlipidaemia, smoking status and the use of antithrombotic therapy were assessed at baseline and 6 months later. The findings were compared with targets from the UK National Clinical Guidelines for Stroke. Results: Baseline and follow-up data were available on 284 patients. The rates of control of vascular risk factors improved only slightly during follow-up. Blood pressure was below target levels in only 69 (24%) at baseline and 79 (28%) at 6 months, and serum cholesterol was below target levels in only 55 (19%) at baseline and 63 (22%) at 6 months. At baseline, 55 ( 19%) were smokers, of whom 12 (22%) had quit at 6 months. Anticoagulant therapy was prescribed in 19 of 37 patients (51%) in atrial fibrillation at 6 months. Antiplatelet therapy was prescribed in 90% of patients in sinus rhythm. Conclusions: Despite the identification of vascular risk factors at the time of clinic or surgery, 6 months later these risk factors remain poorly addressed. More effective methods of managing vascular risk in these patients are needed. Copyright (c) 2007 S. Karger AG, Basel.
引用
收藏
页码:156 / 161
页数:6
相关论文
共 32 条
[1]  
[Anonymous], 1994, BMJ, V308, P81, DOI [10.1136/bmj.308.6921.81, DOI 10.1136/BMJ.308.6921.81]
[2]   Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis [J].
Barnett, HJM ;
Taylor, W ;
Eliasziw, M ;
Fox, AJ ;
Ferguson, GG ;
Haynes, RB ;
Rankin, RN ;
Clagett, GP ;
Hachinski, VC ;
Sackett, DL ;
Thorpe, KE ;
Meldrum, HE ;
Spence, JD .
NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (20) :1415-1425
[3]  
Bero LA, 1998, BMJ-BRIT MED J, V317, P465
[4]   Why don't physicians follow clinical practice guidelines? A framewouk for improvement [J].
Cabana, MD ;
Rand, CS ;
Powe, NR ;
Wu, AW ;
Wilson, MH ;
Abboud, PAC ;
Rubin, HR .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 282 (15) :1458-1465
[5]   Stroke in Devon: knowledge was good, but action was poor [J].
Carroll, C ;
Hobart, J ;
Fox, C ;
Teare, L ;
Gibson, J .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2004, 75 (04) :567-571
[6]  
Collins R, 2002, LANCET, V360, P7, DOI 10.1016/S0140-6736(02)09327-3
[7]  
Department of Health, 2003, INV GEN PRACT NEW GE
[8]   Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial [J].
Diener, HC ;
Bogousslavsky, J ;
Brass, LM ;
Cimminiello, C ;
Csiba, L ;
Kaste, M ;
Leys, D ;
Matias-Guiv, J ;
Rupprecht, HJ .
LANCET, 2004, 364 (9431) :331-337
[9]   Anticoagulant patient information material is written at high readability levels [J].
Estrada, CA ;
Hryniewicz, MM ;
Higgs, VB ;
Collins, C ;
Byrd, JC .
STROKE, 2000, 31 (12) :2966-2970
[10]   Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European carotid surgery trial (ECST) [J].
Farrell, B ;
Fraser, A ;
Sandercock, P ;
Slattery, J ;
Warlow, CP .
LANCET, 1998, 351 (9113) :1379-1387