Epidemiology and pathogenesis of Neisseria meningitidis

被引：162

作者：

Tzeng, YL ^{[1
]}

Stephens, DS

机构：

[1] Emory Univ, Sch Med, Dept Med, Atlanta, GA 30322 USA

[2] Emory Univ, Sch Med, Dept Microbiol & Immunol, Atlanta, GA 30322 USA

[3] Vet Affairs Med Ctr, Res Serv, Labs Microbial Pathogenesis, Atlanta, GA 30033 USA

来源：

MICROBES AND INFECTION | 2000年 / 2卷 / 06期

关键词：

Neisseria meningitidis; meningitis; pathogenesis; epidemiology; virulence factors;

D O I：

10.1016/S1286-4579(00)00356-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Neisseria meningitidis, an exclusive pathogen of humans, remains the leading worldwide cause of meningitis and fatal sepsis, usually in otherwise healthy individuals. In recent years, significant advances have improved our understanding of the epidemiology and genetic basis of meningococcal disease and led to progress in the development of the next generation of meningococcal vaccines. This review summarizes current knowledge of the human susceptibility to and the epidemiology and molecular pathogenesis of meningococcal disease. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

引用

收藏

页码：687 / 700

页数：14

相关论文

共 139 条

[1] CLONAL SPREAD OF SEROGROUP-A MENINGOCOCCI - A PARADIGM FOR THE ANALYSIS OF MICROEVOLUTION IN BACTERIA [J].

ACHTMAN, M .

MOLECULAR MICROBIOLOGY, 1994, 11 (01) :15-22

[2] VARIATION IN CLASS-5 PROTEIN EXPRESSION BY SEROGROUP-A MENINGOCOCCI DURING A MENINGITIS EPIDEMIC [J].

ACHTMAN, M ;

WALL, RA ;

BOPP, M ;

KUSECEK, B ;

MORELLI, G ;

SAKEN, E ;

HASSANKING, M .

JOURNAL OF INFECTIOUS DISEASES, 1991, 164 (02) :375-382

[3] Outer membrane vesicle vaccines made from short-chain lipopolysaccharide mutants of serogroup B Neisseria meningitidis: effect of the carbohydrate chain length on the immune response [J].

Andersen, SR ;

Bjune, G ;

Hoiby, EA ;

Michaelsen, TE ;

Aase, A ;

Rye, U ;

Jantzen, E .

VACCINE, 1997, 15 (11) :1225-1234

[4] SAFETY AND IMMUNOGENICITY OF MENINGOCOCCAL A-POLYSACCHARIDE AND C-POLYSACCHARIDE CONJUGATE VACCINE IN ADULTS [J].

ANDERSON, EL ;

BOWERS, T ;

MINK, CM ;

KENNEDY, DJ ;

BELSHE, RB ;

HARAKEH, H ;

PAIS, L ;

HOLDER, P ;

CARLONE, GM .

INFECTION AND IMMUNITY, 1994, 62 (08) :3391-3395

[5] Antigenic-variation of the class I outer membrane protein in hyperendemic Neisseria meningitidis strains in the Netherlands [J].

Bart, A ;

Dankert, J ;

van der Ende, A .

INFECTION AND IMMUNITY, 1999, 67 (08) :3842-3846

[6] Promoter strength influences phase variation of neisserial opa genes [J].

Belland, RJ ;

Morrison, SG ;

Carlson, JH ;

Hogan, DM .

MOLECULAR MICROBIOLOGY, 1997, 23 (01) :123-135

[7] STRUCTURAL DETERMINATION OF POLYSACCHARIDE ANTIGENS OF NEISSERIA-MENINGITIDIS SEROGROUP-Y, SEROGROUP-W-135, AND SEROGROUP-BO [J].

BHATTACHARJEE, AK ;

JENNINGS, HJ ;

KENNY, CP ;

MARTIN, A ;

SMITH, ICP .

CANADIAN JOURNAL OF BIOCHEMISTRY, 1976, 54 (01) :1-8

[8] SECRETOR STATUS, SMOKING AND CARRIAGE OF NEISSERIA-MENINGITIDIS [J].

BLACKWELL, CC ;

WEIR, DM ;

JAMES, VS ;

TODD, WTA ;

BANATVALA, N ;

CHAUDHURI, AKR ;

GRAY, HG ;

THOMSON, EJ ;

FALLON, RJ .

EPIDEMIOLOGY AND INFECTION, 1990, 104 (02) :203-209

[9]

Blake M., 1987, BACTERIAL OUTER MEMB, P377

[10] NEISSERIA-MENINGITIDIS WITH DECREASED SUSCEPTIBILITY TO PENICILLIN IN SASKATCHEWAN, CANADA [J].

BLONDEAU, JM ;

ASHTON, FE ;

ISAACSON, M ;

YASCHUCK, Y ;

ANDERSON, C ;

DUCASSE, G .

JOURNAL OF CLINICAL MICROBIOLOGY, 1995, 33 (07) :1784-1786

← 1 2 3 4 5 6 7 8 9 10 →