Highly enantioselective nitroaldol reaction catalyzed by new chiral copper complexes

被引：157

作者：

Bandini, Marco ^{[1
]}

Piccinelli, Fabio ^{[1
]}

Tommasi, Simona ^{[1
]}

Umani-Ronchi, Achille ^{[1
]}

Ventrici, Caterina ^{[1
]}

机构：

[1] Univ Bologna, Dipartimento Chim G Ciamician, I-40126 Bologna, Italy

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 06期

关键词：

D O I：

10.1039/b613019d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Remarkable generality in scope of DATs/Cu catalysts for enantioselective nitroaldol reaction is described; excellent levels of stereoinduction are recorded for a range of aldehydes (ee 81-99%, 17 examples) and the possibility to employ the present catalytic system as the key step for the preparation of highly functionalized tetrahydro-isoquinolines is demonstrated.

引用

页码：616 / 618

页数：3

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