Simple and efficient chemoselective mild deprotection of acetals and ketals using cerium(III) triflate

被引：64

作者：

Dalpozzo, R

De Nino, A

Maiuolo, L

Procopio, A ^{[1
]}

Tagarelli, A

Sindona, G

Bartoli, G

机构：

[1] Univ Calabria, Dipartimento Chim, I-87030 Arcavacata Di Rende, CS, Italy

[2] Dipartimento Chim Organ A Mangini, I-40136 Bologna, Italy

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 25期

关键词：

D O I：

10.1021/jo0260387

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new and chemoselective method for the cleavage of alkyl and cyclic acetals and ketals at room temperature in wet nitromethane by using catalytic cerium(III) trifluoromethane sulfonate is presented. The high yields, the observed selectivity, the very gentle reaction conditions, and the almost neutral pH make this procedure particularly attractive for multistep synthesis.

引用

页码：9093 / 9095

页数：3

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