Nuclear anarchy: asynchronous mitosis in multinucleated fungal hyphae

被引:54
作者
Gladfelter, Amy S. [1 ]
机构
[1] Dartmouth Coll, Dept Biol, Hanover, NH 03755 USA
基金
美国国家科学基金会;
关键词
D O I
10.1016/j.mib.2006.09.002
中图分类号
Q93 [微生物学];
学科分类号
071005 [微生物学]; 100705 [微生物与生化药学];
摘要
Multinucleated cells are found in diverse contexts and include filamentous fungi, developing insect embryos, skeletal muscle and metastasizing tumor cells. Some multinucleated cells such as those in muscles arise from cell fusion events, but many are formed through specialized cell cycles in which nuclear and cell division are uncoupled. Recent work in the fungus Ashbya gossypii illustrates how unique spatial and temporal regulation of conserved cell cycle regulators directs mitosis in multinucleated cells.
引用
收藏
页码:547 / 552
页数:6
相关论文
共 37 条
[2]
BEHAVIOR OF SPINDLES AND SPINDLE PLAQUES IN CELL-CYCLE AND CONJUGATION OF SACCHAROMYCES-CEREVISIAE [J].
BYERS, B ;
GOETSCH, L .
JOURNAL OF BACTERIOLOGY, 1975, 124 (01) :511-523
[3]
DUPLICATION OF SPINDLE PLAQUES AND INTEGRATION OF YEAST-CELL CYCLE [J].
BYERS, B ;
GOETSCH, L .
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1973, 38 :123-131
[4]
Byers B., 1981, The Molecular Biology of the Yeast Saccharomyces: Life Cycle and Inheritance, P59
[5]
SYNCHRONOUS NUCLEAR DIVISION AND SEPTATION IN ASPERGILLUS-NIDULANS [J].
CLUTTERBUCK, AJ .
JOURNAL OF GENERAL MICROBIOLOGY, 1970, 60 :133-+
[6]
Partial nuclear pore complex disassembly during closed mitosis in Aspergillus nidulans [J].
De Souza, CPC ;
Osmani, AH ;
Hashmi, SB ;
Osmani, S .
CURRENT BIOLOGY, 2004, 14 (22) :1973-1984
[7]
De Souza CPC, 2003, GENETICS, V165, P1071
[8]
The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome [J].
Dietrich, FS ;
Voegeli, S ;
Brachat, S ;
Lerch, A ;
Gates, K ;
Steiner, S ;
Mohr, C ;
Pöhlmann, R ;
Luedi, P ;
Choi, SD ;
Wing, RA ;
Flavier, A ;
Gaffney, TD ;
Phillippsen, P .
SCIENCE, 2004, 304 (5668) :304-307
[9]
Neurospora crassa supersuppressor mutants are amber codon-specific [J].
Fang, P ;
Wu, C ;
Sachs, MS .
FUNGAL GENETICS AND BIOLOGY, 2002, 36 (03) :167-175
[10]
Asynchronous nuclear division cycles in multinucleated cells [J].
Gladfelter, AS ;
Hungerbuehler, AK ;
Philippsen, P .
JOURNAL OF CELL BIOLOGY, 2006, 172 (03) :347-362