Reliability of the North Star Ambulatory Assessment in a multicentric setting

被引：177

作者：

Mazzone, E. S. ^{[1
]}

Messina, S. ^{[1
,2
]}

Vasco, G. ^{[1
]}

Main, M. ^{[3
]}

Eagle, M. ^{[17
]}

D'Amico, A. ^{[4
,5
]}

Doglio, L. ^{[6
]}

Politano, L. ^{[7
]}

Cavallaro, F. ^{[2
]}

Frosini, S. ^{[8
]}

Bello, L. ^{[9
]}

Magri, F. ^{[10
]}

Corlatti, A. ^{[11
]}

Zucchini, E. ^{[12
]}

Brancalion, B. ^{[13
]}

Rossi, F. ^{[14
]}

Ferretti, M. ^{[15
]}

Motta, M. G. ^{[15
]}

Cecio, M. R. ^{[7
]}

Berardinelli, A. ^{[15
]}

Alfieri, P. ^{[1
,4
,5
]}

Mongini, T. ^{[14
]}

Pini, A. ^{[12
]}

Astrea, G. ^{[8
]}

Battini, R. ^{[8
]}

Comi, G. ^{[10
]}

Pegoraro, E. ^{[9
]}

Morandi, L. ^{[11
]}

Pane, M. ^{[1
]}

Angelini, C. ^{[9
]}

Bruno, C. ^{[6
]}

Villanova, M. ^{[13
]}

Vita, G. ^{[2
]}

Donati, M. A. ^{[16
]}

Bertini, E. ^{[4
,5
]}

Mercuri, E. ^{[1
,3
]}

机构：

[1] Catholic Univ, Dept Paediat Neurol, Rome, Italy

[2] Univ Messina, Dept Neurosci Psychiat & Anaesthesiol, Messina, Italy

[3] Inst Child Hlth, Dubowitz Neuromuscular Unit, London, England

[4] Bambino Gesu Pediat Hosp, Dept Lab Med, Mol Med Unit, Rome, Italy

[5] Bambino Gesu Pediat Hosp, Dept Pediat Neuropsychiat, Rome, Italy

[6] Ist Giannina Gaslini, Neuromuscular Dis Unit, I-16148 Genoa, Italy

[7] Univ Naples 2, Dipartimento Med Chirurg Internist Clin & Sperime, Naples, Italy

[8] Univ Pisa, Dept Paediat Neurol, Stella Maris Inst, I-56100 Pisa, Italy

[9] Univ Padua, Dept Neurosci, Padua, Italy

[10] Osped Maggiore, IRCCS Fdn, Policlin Mangiagalli & Regina Elena, Milan, Italy

[11] Neurol Inst C Besta, Milan, Italy

[12] Maggiore Hosp, Child Neurol & Psychiat Unit, Bologna, Italy

[13] Nigrisoli Hosp, Bologna, Italy

[14] Univ Turin, Neuromuscular Ctr, SG Battista Hosp, I-10124 Turin, Italy

[15] Univ Pavia, IRCCS C Mondino Fdn, I-27100 Pavia, Italy

[16] Meyer Hosp, Metab & Neuromuscular Unit, Florence, Italy

[17] Univ Newcastle, Inst Human Genet, Newcastle Upon Tyne, Tyne & Wear, England

来源：

NEUROMUSCULAR DISORDERS | 2009年 / 19卷 / 07期

关键词：

Duchenne Muscular Dystrophy; Outcome; Function; DUCHENNE MUSCULAR-DYSTROPHY; NEUROMUSCULAR DISEASES; CHILDREN; SCALE;

D O I：

10.1016/j.nmd.2009.06.368

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

The aim of this study was to investigate the suitability of the North Star Ambulatory Assessment as a possible outcome measure in multicentric clinical trials. More specifically we wished to investigate the level of training needed for achieving a good interobserver reliability in a multicentric setting. The scale was specifically designed for ambulant children with Duchenne Muscular Dystrophy and includes 17 items that are relevant for this cohort. Thirteen Italian centers participated in the study. In the first phase of the study we provided two training videos and an example of the scale performed on a child. After the first session of training, all the 13 examiners were asked to send a video with an assessment performed in their centre and to score all the videos collected. There were no difficulties in performing the items and in obtaining adequate videos with a hand held camera but the results showed a poor interobserver reliability (<.5). After a second training session with review and discussion of the videos previously scored, the same examiners were asked to score three new videos. The results of this session had an excellent interobserver reliability (.995). The level of agreement was maintained even when the same videos were rescored after a month, showing a significant intra-observer reliability (.95). Our results suggest that the NSAA is a test that can be easily performed, completed in 10 min and call be used in a multicentric setting, providing that adequate training is administered. (C) 2009 Published by Elsevier B.V.

引用

页码：458 / 461

页数：4

共 20 条

[1]

Bérard C, 2006, REV NEUROL-FRANCE, V162, P485

[2]

A motor function measure scale for neuromuscular diseases.: Construction and validation study [J].