Pregnancy-associated Cushing's syndrome secondary to a luteinizing hormone/human chorionic gonadotropin receptor-positive adrenal carcinoma

被引：37

作者：

Wy, LA ^{[1
]}

Carlson, HE ^{[1
]}

Kane, P ^{[1
]}

Li, X ^{[1
]}

Lei, ZM ^{[1
]}

Rao, CV ^{[1
]}

机构：

[1] SUNY Stony Brook, Div Endocrinol, Dept Med, Stony Brook, NY 11794 USA

来源：

GYNECOLOGICAL ENDOCRINOLOGY | 2002年 / 16卷 / 05期

关键词：

Cushing syndrome; adrenal cortex neoplasms; receptors; gonadotropin; pregnancy;

D O I：

10.1080/713603116

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cushing's syndrome occurring during pregnancy is frequently due to an adrenal neoplasm. Adrenal gland tumors occasionally respond to luteinizing hormone (LH) or human chorionic gonadotropin (hCG). We report. a case of Cushing's syndrome during and following pregnancy due to an adrenal carcinoma which expressed the LH/hCG receptor. The presence of these receptors may have led to the growth and function of the tumor during pregnancy.

引用

页码：413 / 417

页数：5

共 16 条

[1] VIRILIZING ADRENOCORTICAL ADENOMA RESPONSIVE TO GONADOTROPIN [J].

BLICHERTTOFT, M ;

VEJLSTED, H ;

KEHLET, H ;

ALBRECHTSEN, R .

ACTA ENDOCRINOLOGICA, 1975, 78 (01) :77-85

[2] Presence of a Gsα mutation in an adrenal tumor expressing LH/hCG receptors and clinically associated with Cushing's syndrome [J].

Bugalho, MJM ;

Li, X ;

Rao, CV ;

Soares, J ;

Sobrinho, LG .

GYNECOLOGICAL ENDOCRINOLOGY, 2000, 14 (01) :50-54

[3] GONADOTROPIN RESPONSIVE TESTOSTERONE PRODUCING ADRENOCORTICAL ADENOMA AND HIGH GONADOTROPIN-LEVELS IN AN ELDERLY WOMAN [J].

DELANGE, WE ;

PRATT, JJ ;

DOORENBOS, H .

CLINICAL ENDOCRINOLOGY, 1980, 12 (01) :21-28

[4] GONADOTROPIN-RESPONSIVE ADRENOCORTICAL ADENOMA [J].

GIVENS, JR ;

ANDERSEN, RN ;

WISER, WL ;

COLEMAN, SA ;

FISH, SA .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1974, 38 (01) :126-133

[5] Ectopic and abnormal hormone receptors in adrenal Cushing's syndrome [J].

Lacroix, A ;

N'Diaye, N ;

Tremblay, J ;

Hamet, P .

ENDOCRINE REVIEWS, 2001, 22 (01) :75-110

[6] Leuprolide acetate therapy in luteinizing hormone-dependent Cushing's syndrome. [J].

Lacroix, A ;

Hamet, P ;

Boutin, J .

NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (21) :1577-1581

[7] TESTOSTERONE-PRODUCING ADRENAL-CORTICAL ADENOMA IN AN ELDERLY WOMAN [J].

LARSON, BA ;

VANDERLAAN, WP ;

JUDD, HL ;

MCCULLOUGH, DL .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1976, 42 (05) :882-887

[8] TESTOSTERONE-SECRETING VIRILIZING ADRENAL ADENOMA WITH HUMAN CHORIONIC-GONADOTROPIN RECEPTORS AND 21-HYDROXYLASE DEFICIENCY [J].

LEINONEN, P ;

RANTA, T ;

SIEGBERG, R ;

PELKONEN, R ;

HEIKKILA, P ;

KAHRI, A .

CLINICAL ENDOCRINOLOGY, 1991, 34 (01) :31-35

[9]

MATSUKURA S, 1980, CANCER RES, V40, P3768

[10] INVITRO SYNTHESIS OF STEROIDS BY A FEMINIZING ADRENOCORTICAL CARCINOMA - EFFECT OF PROLACTIN AND OTHER PROTEIN HORMONES [J].

MILLINGTON, DS ;

GOLDER, MP ;

COWLEY, T ;

LONDON, D ;

ROBERTS, H ;

BUTT, WR ;

GRIFFITHS, K .

ACTA ENDOCRINOLOGICA, 1976, 82 (03) :561-571

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