Combination of 5-fluorouracil and radiation in esophageal cancer

被引：8

作者：

Herskovic, A ^{[1
]}

AlSarraf, M ^{[1
]}

机构：

[1] PROVIDENCE CANC CTR,SOUTHFIELD,MI

来源：

SEMINARS IN RADIATION ONCOLOGY | 1997年 / 7卷 / 04期

关键词：

D O I：

10.1016/S1053-4296(97)80027-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A review of the trends in the clinical practice of esophageal cancer treatment is presented. The preponderance of evidence indicates that concomitant chemotherapy and radiation is superior to either modality above. Chemotherapy usually, but not invariably, consists of 5-fluorouracil (5-FU) and cisplatin; radiotherapy is usually 50 Gy. Attempts to escalate to higher dose by external-beam boost or brachytherapy is still experimental. Combination treatment with surgery is also successful, but the inclusion of esophagectomy in the treatment is not universally accepted and is unlikely to be tested. A suggestion to base treatment selection on response is proposed.

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页码：283 / 290

页数：8

相关论文

共 63 条

[1] PROLONGED CHEMOTHERAPY FOR LOCALIZED SQUAMOUS CARCINOMA OF THE ESOPHAGUS [J].

AJANI, JA ;

RYAN, B ;

RICH, TA ;

MCMURTREY, M ;

ROTH, JA ;

DECARO, L ;

LEVIN, B ;

MOUNTAIN, C .

EUROPEAN JOURNAL OF CANCER, 1992, 28A (4-5) :880-884

[2] INTENSIVE PREOPERATIVE CHEMOTHERAPY WITH COLONY-STIMULATING FACTOR FOR RESECTABLE ADENOCARCINOMA OF THE ESOPHAGUS OR GASTROESOPHAGEAL JUNCTION [J].

AJANI, JA ;

ROTH, JA ;

RYAN, MB ;

PUTNAM, JB ;

PAZDUR, R ;

LEVIN, B ;

GUTTERMAN, JU ;

MCMURTREY, M .

JOURNAL OF CLINICAL ONCOLOGY, 1993, 11 (01) :22-28

[3] EVALUATION OF PREOPERATIVE AND POSTOPERATIVE CHEMOTHERAPY FOR RESECTABLE ADENOCARCINOMA OF THE ESOPHAGUS OR GASTROESOPHAGEAL JUNCTION [J].

AJANI, JA ;

ROTH, JA ;

RYAN, B ;

MCMURTREY, M ;

RICH, TA ;

JACKSON, DE ;

ABBRUZZESE, JL ;

LEVIN, B ;

DECARO, L ;

MOUNTAIN, C .

JOURNAL OF CLINICAL ONCOLOGY, 1990, 8 (07) :1231-1238

[4]

ALSARRAF M, 1996, P AN M AM SOC CLIN, V15, P464

[5]

ARAUJO CMM, 1991, CANCER, V67, P2258, DOI 10.1002/1097-0142(19910501)67:9<2258::AID-CNCR2820670908>3.0.CO

[6]

2-G

[7] Concurrent radiation therapy and chemotherapy followed by esophagectomy for localized esophageal carcinoma [J].

Bates, BA ;

Detterbeck, FC ;

Bernard, SA ;

Qaqish, BF ;

Tepper, JE .

JOURNAL OF CLINICAL ONCOLOGY, 1996, 14 (01) :156-163

[8] LONG-TERM FOLLOW-UP OF NEOADJUVANT CHEMOTHERAPY WITH 5-FLUOROURACIL AND CISPLATIN WITH SURGICAL RESECTION AND POSSIBLE POSTOPERATIVE RADIOTHERAPY AND OR CHEMOTHERAPY IN SQUAMOUS-CELL CARCINOMA OF THE ESOPHAGUS [J].

CAREY, RW ;

HILGENBERG, AD ;

WILKINS, EW ;

CHOI, NC ;

MATHISEN, DJ ;

GRILLO, HC ;

WAIN, JC ;

LOGAN, DL ;

BROMBERG, C .

CANCER INVESTIGATION, 1993, 11 (02) :99-105

[9] CONCOMITANT 5-FLUOROURACIL INFUSION, MITOMYCIN-C AND RADICAL RADIATION-THERAPY IN ESOPHAGEAL SQUAMOUS-CELL CARCINOMA [J].

CHAN, A ;

WONG, A ;

ARTHUR, K .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1989, 16 (01) :59-65

[10] LONG-TERM RESULTS OF INFUSIONAL 5-FU, MITOMYCIN-C, AND RADIATION AS PRIMARY MANAGEMENT OF ESOPHAGEAL-CARCINOMA [J].

COIA, LR ;

ENGSTROM, PF ;

PAUL, AR ;

STAFFORD, PM ;

HANKS, GE .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1991, 20 (01) :29-36

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