Immunizations in Patients with Inflammatory Bowel Disease

Patients receiving immunosuppressive therapies may be at increased risk for complications of vaccine preventable diseases, including influenza, varicella. and pneumococcus. However, studies suggest that patients with chronic illness may be inadequately immunized. In part. this is because of a paucity OF formal vaccine studies in immune compromised populations. This review discusses the methods One uses to assess vaccine efficacy and provides an Update Oil currently known data oil the vaccine antibody responses in immune compromised hosts. Currently published Studies suggest that influenza vaccine call be safely administered to patients with BD oil immunosuppression, and is effective in the majority of patients. Further formal Studies with other inactivated vaccines (e.g., pneumococcal vaccine, meningitis vaccine) should be conducted. While sonic Studies in immune compromised hosts Suggest the live attenuated varicella vaccine can be given without adverse events, administration of this vaccine in patients oil immunosuppression remains controversial.