Perfect simulation from nonneutral population genetic models: Variable population size and population subdivision

被引：6

作者：

Fearnhead, Paul ^{[1
]}

机构：

[1] Univ Lancaster, Dept Math & Stat, Lancaster LA1 4YF, England

来源：

GENETICS | 2006年 / 174卷 / 03期

关键词：

D O I：

10.1534/genetics.106.060681

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We show how the idea of monotone coupling from the past can produce simple algorithms for simulating samples at a nonneutral locus under a range of demographic models. We specifically consider a biallelic locus and either a general variable population size mode or a general migration model for population subdivision. We investigate the effect of demography on the efficacy of selection and the effect of selection on genetic divergence between populations.

引用

页码：1397 / 1406

页数：10

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