Evaluation of the antiviral activity of kaempferol and its glycosides against human cytomegalovirus

被引：40

作者：

Mitrocotsa, D

Mitaku, S ^{[1
]}

Axarlis, S

Harvala, C

Malamas, M

机构：

[1] Univ Athens, Sch Pharm, Div Pharmacognosy, GR-15771 Athens, Greece

[2] Hellen Pasteur Inst, Athens, Greece

[3] Univ Ioannina, Sch Med, Dept Pharmacol, GR-45110 Ioannina, Greece

来源：

PLANTA MEDICA | 2000年 / 66卷 / 04期

关键词：

D O I：

10.1055/s-2000-8550

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The antiviral activity of seven flavonoids, belonging to the kaempferol series. was evaluated against human cytomegalovirus (HCMV) by a rapid method of detection of the immediate-early (IE) antigen, induced by the virus in infected cells. Flavonoids bearing acyl substituents were found to be the most active compounds.

引用

页码：377 / 379

页数：3

共 21 条

[1]

AKIYAMA T, 1987, J BIOL CHEM, V262, P5592

[2]

ALFORD CA, 1990, VIROLOGY, P1891

[3] RAPID DETECTION OF HUMAN CYTOMEGALO-VIRUS IN THE URINE OF HUMANS [J].