Prevalence of acquired AmpC β-lactamases in Enterobacteriaceae lacking inducible chromosomal ampC genes at a Spanish hospital from 1999 to 2007

被引：39

作者：

Mata, C. ^{[1
,2
]}

Miro, E. ^{[1
]}

Rivera, A. ^{[1
,2
]}

Mirelis, B. ^{[1
]}

Coll, P. ^{[1
,2
]}

Navarro, F. ^{[1
,2
]}

机构：

[1] Hosp Santa Creu & Sant Pau, Microbiol Serv, Barcelona, Spain

[2] Univ Autonoma Barcelona, Unitat Microbiol, Dept Genet & Microbiol, Bellaterra, Spain

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2010年 / 16卷 / 05期

关键词：

AmpC beta-lactamases; antimicrobial resistance mechanism; epidemiology of resistance; PLASMID-MEDIATED AMPC; ESCHERICHIA-COLI; KLEBSIELLA-PNEUMONIAE; PROTEUS-MIRABILIS; CTX-M; STRAINS; RESISTANCE; SPAIN;

D O I：

10.1111/j.1469-0691.2009.02864.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

P>In 2007, a significant increase in acquired ampC genes in Enterobacteriaceae from 0.06% in 1999 to 1.3% was observed. Proteus mirabilis showed the highest prevalence (0.95%) and CMY-2 was the most prevalent AmpC enzyme (66.7%). Other enzymes such as CMY-4, DHA-1, ACC-1, and three new enzymes called CMY-25, CMY-27 and CMY-40 were detected. Seven out of the 117 isolates (6%) also produced an extended-spectrum beta-lactamase. As acquired AmpC enzymes are likely to become a serious public health issue worldwide, close surveillance is necessary to curb their spread.

引用

页码：473 / 476

页数：4

共 17 条

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