Effects of medicinal plants on Alzheimer's disease and memory deficits

被引:122
作者
Akram, Muhammad [1 ]
Nawaz, Allah [2 ]
机构
[1] Univ Poonch, Fac Med & Hlth Sci, Dept Eastern Med & Surg, Rawalakot, Azad Jammu & Ka, Pakistan
[2] Univ Toyama, Fac Med, Dept Internal Med 1, Toyama, Japan
关键词
nerve regeneration; memory; Alzheimer's disease; medicinal plants; efficacy; literature review; neural regeneration; GINKGO-BILOBA EXTRACT; CROCUS-SATIVUS L; MAGNOLIA-OFFICINALIS; RAT MODEL; CHOLINESTERASE-INHIBITORS; CONVOLVULUS-PLURICAULIS; CHEMICAL-CONSTITUENTS; COGNITIVE IMPAIRMENT; ENHANCEMENT ACTIVITY; GLYCYRRHIZA-GLABRA;
D O I
10.4103/1673-5374.205108
中图分类号
Q2 [细胞生物学];
学科分类号
071013 [干细胞生物学];
摘要
Alzheimer's disease is an age-related neurodegenerative disorder characterized by memory deficits. Various studies have been carried out to find therapeutic approaches for Alzheimer's disease. However, the proper treatment option is still not available. There is no cure for Alzheimer's disease, but symptomatic treatment may improve the memory and other dementia related problems. Traditional medicine is practiced worldwide as memory enhancer since ancient times. Natural therapy including herbs and medicinal plants has been used in the treatment of memory deficits such as dementia, amnesia, as well as Alzheimer's disease since a long time. Medicinal plants have been used in different systems of medicine, particularly Unani system of medicines and exhibited their powerful roles in the management and cure of memory disorders. Most of herbs and plants have been chemically evaluated and their efficacy has also been proven in clinical trials. However, the underlying mechanisms of actions are still on the way. In this paper, we have reviewed the role of different medicinal plants that play an important role in the treatment of Alzheimer's disease and memory deficits using conventional herbal therapy.
引用
收藏
页码:660 / 670
页数:11
相关论文
共 150 条
[1]
Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases [J].
Aggarwal, Bharat B. ;
Harikumar, Kuzhuvelil B. .
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2009, 41 (01) :40-59
[2]
Neuropharmacological Review of the Nootropic Herb Bacopa monnieri [J].
Aguiar, Sebastian ;
Borowski, Thomas .
REJUVENATION RESEARCH, 2013, 16 (04) :313-326
[3]
Acetylcholine and memory-enhancing activity of Ficus racemosa bark [J].
Ahmed, Faiyaz ;
Chandra, J. N. Narendra Sharath ;
Manjunath, S. .
PHARMACOGNOSY RESEARCH, 2011, 3 (04) :246-249
[4]
Salvia officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease:: a double blind, randomized and placebo-controlled trial [J].
Akhondzadeh, S ;
Noroozian, M ;
Mohammadi, M ;
Ohadinia, S ;
Jamshidi, AH ;
Khani, M .
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2003, 28 (01) :53-59
[5]
Akhondzadeh S, 2003, FOOD PROT, V6, P625
[6]
A 22-week, multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer's disease [J].
Akhondzadeh, Shahin ;
Sabet, Mehdi Shafiee ;
Harirchian, Mohammad Hossein ;
Togha, Mansoreh ;
Cheraghmakani, Hamed ;
Razeghi, Soodeh ;
Hejazi, Seyyed Shamssedin ;
Yousefi, Mohammad Hossein ;
Alimardani, Roozbeh ;
Jamshidi, Amirhossein ;
Rezazadeh, Shams-Ali ;
Yousefi, Aboulghasem ;
Zare, Farhad ;
Moradi, Atbin ;
Vossoughi, Ardalan .
PSYCHOPHARMACOLOGY, 2010, 207 (04) :637-643
[7]
Amala S, 2012, INT J ALZHEIMER DIS, V38, P974
[8]
Ambawade S, 2009, J NAT REMED, V2, P130
[9]
Asgarpanah J., 2012, African Journal of Biotechnology, V11, P12787
[10]
AsuthoshAgarwal S., 2000, Indian Journal of Pharmacology, V34, P339