The Neurobiology of Decision: Consensus and Controversy

被引:583
作者
Kable, Joseph W. [1 ]
Glimcher, Paul W. [2 ]
机构
[1] Univ Penn, Dept Psychol, Philadelphia, PA 19104 USA
[2] NYU, Ctr Neuroecon, New York, NY 10003 USA
基金
美国国家卫生研究院;
关键词
DOPAMINE NEURONS ENCODE; DORSOLATERAL PREFRONTAL CORTEX; POSTERIOR PARIETAL CORTEX; ORBITOFRONTAL CORTEX; NEURAL BASIS; CINGULATE CORTEX; PERCEPTUAL DECISION; PREDICTION ERRORS; REWARD PREDICTION; BASAL GANGLIA;
D O I
10.1016/j.neuron.2009.09.003
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We review and synthesize recent neurophysiological studies of decision making in humans and nonhuman primates. From these studies, the basic outline of the neurobiological mechanism for primate choice is beginning to emerge. The identified mechanism is now known to include a multicomponent valuation stage, implemented in ventromedial prefrontal cortex and associated parts of striatum, and a choice stage, implemented in lateral prefrontal and parietal areas. Neurobiological studies of decision making are beginning to enhance our understanding of economic and social behavior as well as our understanding of significant health disorders where people's behavior plays a key role.
引用
收藏
页码:733 / 745
页数:13
相关论文
共 121 条
[1]   Cognitive neuroscience of human social behaviour [J].
Adolphs, R .
NATURE REVIEWS NEUROSCIENCE, 2003, 4 (03) :165-178
[2]   Intentional maps in posterior parietal cortex [J].
Andersen, RA ;
Buneo, CA .
ANNUAL REVIEW OF NEUROSCIENCE, 2002, 25 :189-220
[3]  
[Anonymous], 1982, Visual perception
[4]  
Balleine BW, 2009, NEUROECONOMICS: DECISION MAKING AND THE BRAIN, P367, DOI 10.1016/B978-0-12-374176-9.00024-5
[5]   Goal-directed instrumental action: contingency and incentive learning and their cortical substrates [J].
Balleine, BW ;
Dickinson, A .
NEUROPHARMACOLOGY, 1998, 37 (4-5) :407-419
[6]   Prefrontal cortex and decision making in a mixed-strategy game [J].
Barraclough, DJ ;
Conroy, ML ;
Lee, D .
NATURE NEUROSCIENCE, 2004, 7 (04) :404-410
[7]  
Basso MA, 1998, J NEUROSCI, V18, P7519
[8]   Statistics of midbrain dopamine neuron spike trains in the awake primate [J].
Bayer, Hannah M. ;
Lau, Brian ;
Glimcher, Paul W. .
JOURNAL OF NEUROPHYSIOLOGY, 2007, 98 (03) :1428-1439
[9]   Midbrain dopamine neurons encode a quantitative reward prediction error signal [J].
Bayer, HM ;
Glimcher, PW .
NEURON, 2005, 47 (01) :129-141
[10]   Learning the value of information in an uncertain world [J].
Behrens, Timothy E. J. ;
Woolrich, Mark W. ;
Walton, Mark E. ;
Rushworth, Matthew F. S. .
NATURE NEUROSCIENCE, 2007, 10 (09) :1214-1221