Steric effects on the sydnones reactivity. New sydnones and pyrazoles

被引：36

作者：

Dumitrascu, F ^{[1
]}

Mitan, CI ^{[1
]}

Dumitrescu, D ^{[1
]}

Draghici, C ^{[1
]}

Caproiu, MT ^{[1
]}

机构：

[1] Romanian Acad, Inst Organ Chem CD Nenitzescu, Spl Independentei 202B, Bucharest, Romania

来源：

ARKIVOC | 2002年

关键词：

sydnones; pyrazoles; steric effect; 1,3 dipolar cycloaddition;

D O I：

10.3998/ark.5550190.0003.209

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The sydnones 7a, b and 8a-c gave the corresponding pyrazoles 9a-e by 1,3-dipolar cycloaddition with dimethyl acetylenedicarboxylate (DMAD). The highly sterically hindered 3-(4,6-dibromo-2- methylphenyl)-4-iodosydnone (8d) failed to react with DMAD on heating in boiling xylene. The iodination of sterically hindered sydnone 7b required more drastic reaction conditions than the sydnone 7a.

引用

页码：80 / 86

页数：7

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