Lipid Droplets Finally Get a Little R-E-S-P-E-C-T

被引:826
作者
Farese, Robert V., Jr. [1 ,2 ,3 ]
Walther, Tobias C. [4 ]
机构
[1] Univ Calif San Francisco, Gladstone Inst Cardiovasc Dis, San Francisco, CA 94158 USA
[2] Univ Calif San Francisco, Dept Med, San Francisco, CA 94158 USA
[3] Univ Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94158 USA
[4] Max Planck Inst Biochem, D-82152 Martinsried, Germany
关键词
INFECTIOUS VIRUS; NEUTRAL LIPIDS; CORE PROTEIN; TRIACYLGLYCEROL; BIOGENESIS; STORAGE; METABOLISM; PERILIPIN; YEAST; BIOSYNTHESIS;
D O I
10.1016/j.cell.2009.11.005
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:855 / 860
页数:6
相关论文
共 46 条
[1]  
Altmann R., 1890, Die Elementarorganisem und ihre Bezlehungen zu den Zellen
[2]   COPI Complex Is a Regulator of Lipid Homeostasis [J].
Beller, Mathias ;
Sztalryd, Carole ;
Southall, Noel ;
Bell, Ming ;
Jaeckle, Herbert ;
Auld, Douglas S. ;
Oliver, Brian .
PLOS BIOLOGY, 2008, 6 (11) :2530-2549
[3]  
BLANCHETTEMACKIE EJ, 1995, J LIPID RES, V36, P1211
[4]   SNARE proteins mediate fusion between cytosolic lipid droplets and are implicated in insulin sensitivity [J].
Bostrom, Pontus ;
Andersson, Linda ;
Rutberg, Mikael ;
Perman, Jeanna ;
Lidberg, Ulf ;
Johansson, Bengt R. ;
Fernandez-Rodriguez, Julia ;
Ericson, Johanna ;
Nilsson, Tommy ;
Boren, Jan ;
Olofsson, Sven-Olof .
NATURE CELL BIOLOGY, 2007, 9 (11) :1286-U139
[5]   Disrupting the association of hepatitis C virus core protein with lipid droplets correlates with a loss in production of infectious virus [J].
Boulant, Steeve ;
Targett-Adams, Paul ;
McLauchlan, John .
JOURNAL OF GENERAL VIROLOGY, 2007, 88 :2204-2213
[6]   Structural determinants that target the hepatitis C virus core protein to lipid droplets [J].
Boulant, Steeve ;
Montserret, Roland ;
Hope, R. Graham ;
Ratinier, Maxime ;
Targett-Adams, Paul ;
Lavergne, Jean-Pierre ;
Penin, Francois ;
McLauchlan, John .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (31) :22236-22247
[7]   Perilipin A and the control of triacylglycerol metabolism [J].
Brasaemle, Dawn L. ;
Subramanian, Vidya ;
Garcia, Anne ;
Marcinkiewicz, Amy ;
Rothenberg, Alexis .
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2009, 326 (1-2) :15-21
[8]   TIP47 functions in the biogenesis of lipid droplets [J].
Bulankina, Anna V. ;
Deggerich, Anke ;
Wenzel, Dirk ;
Mutenda, Kudzai ;
Wittmann, Julia G. ;
Rudolph, Markus G. ;
Burger, Koert N. J. ;
Hoening, Stefan .
JOURNAL OF CELL BIOLOGY, 2009, 185 (04) :641-655
[9]   The lipid-droplet proteome reveals that droplets are a protein-storage depot [J].
Cermelli, Silvia ;
Guo, Yi ;
Gross, Steven P. ;
Welte, Michael A. .
CURRENT BIOLOGY, 2006, 16 (18) :1783-1795
[10]   Identification of mouse Prp19p as a lipid droplet-associated protein and its possible involvement in the biogenesis of lipid droplets [J].
Cho, Si Young ;
Shin, Eui Seok ;
Park, Pil Joon ;
Shin, Dong Wook ;
Chang, Hui Kyoung ;
Kim, Daegun ;
Lee, Hyoung Ho ;
Lee, Jeong Ho ;
Kim, Shin Hyoung ;
Song, Min Jung ;
Chang, Ih-Seop ;
Lee, Ok Sub ;
Lee, Tae Ryong .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (04) :2456-2465