Decision-making functioning as a predictor of treatment outcome in anorexia nervosa

被引：71

作者：

Cavedini, Paolo ^{[1
]}

Zorzi, Claudia ^{[1
]}

Bassi, Tommaso ^{[1
]}

Gorini, Alessandra ^{[1
]}

Baraldi, Clementina ^{[1
]}

Ubbiali, Alessandro ^{[1
]}

Bellodi, Laura ^{[1
]}

机构：

[1] Univ Vita Salute San Raffaele, Sch Psychol, San Raffaele Sci Inst, Dept Neuropsychiat Sci, I-20127 Milan, Italy

来源：

PSYCHIATRY RESEARCH | 2006年 / 145卷 / 2-3期

关键词：

eating disorders; anorexia nervosa; executive function; gambling task; decision-making; treatment predictors;

D O I：

10.1016/j.psychres.2004.12.014

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

The pathological eating behaviour of patients with anorexia nervosa reflects a deficit in planning real-life strategies that can be observed in an experimental setting through the Gambling Task, a tool designed to detect and measure decision-making abilities. We examined the role of Gambling Task performance as a predictor of treatment outcome in anorectic patients, and we evaluated changes in decision-making after clinical improvement. Performance on the Gambling Task was evaluated, and a clinical-nutritional assessment of 38 anorectic patients was carried out before and after a cognitive-behavioural and drug treatment program. Task performance of anorectic patients was compared with that of 30 healthy control participants. Patients who had a better decision-making profile at baseline showed significantly greater improvement in nutritional status. The decision-making deficiency of some anorectic patients is probably linked to those individual features that contribute to the phenomenological expression of the disorder and to its different treatment outcomes. (c) 2005 Elsevier Ireland Ltd. All rights reserved.

引用

页码：179 / 187

页数：9

共 27 条

[1] Long-term follow-up and predictors of clinical outcome in obsessive-compulsive patients treated with serotonin reuptake inhibitors and behavioral therapy [J].

Alonso, P ;

Menchon, JM ;

Pifarre, J ;

Mataix-Cols, D ;

Torres, L ;

Salgado, P ;

Vallejo, J .

JOURNAL OF CLINICAL PSYCHIATRY, 2001, 62 (07) :535-540

[2] Characterization of the decision-making deficit of patients with ventromedial prefrontal cortex lesions [J].

Bechara, A ;

Tranel, D ;

Damasio, H .

BRAIN, 2000, 123 :2189-2202

[3] INSENSITIVITY TO FUTURE CONSEQUENCES FOLLOWING DAMAGE TO HUMAN PREFRONTAL CORTEX [J].

BECHARA, A ;

DAMASIO, AR ;

DAMASIO, H ;

ANDERSON, SW .

COGNITION, 1994, 50 (1-3) :7-15

[4] Morbidity risk for obsessive-compulsive spectrum disorders in first-degree relatives of patients with eating disorders [J].

Bellodi, L ;

Cavallini, MC ;

Bertelli, S ;

Chiapparino, D ;

Riboldi, C ;

Smeraldi, E .

AMERICAN JOURNAL OF PSYCHIATRY, 2001, 158 (04) :563-569

[5] OPERANT-CONDITIONING IN TREATMENT OF ANOREXIA-NERVOSA - REVIEW AND RETROSPECTIVE STUDY OF 11 CASES [J].

BHANJI, S ;

THOMPSON, J .

BRITISH JOURNAL OF PSYCHIATRY, 1974, 124 (FEB) :166-172

[6] Basal-corticofrontal circuits in schizophrenia and obsessive-compulsive disorder: A controlled, double dissociation study [J].

Cavallaro, R ;

Cavedini, P ;

Mistretta, P ;

Bassi, T ;

Angelone, SM ;

Ubbiali, A ;

Bellodi, L .

BIOLOGICAL PSYCHIATRY, 2003, 54 (04) :437-443

[7]

Cavallini MC, 2000, AM J MED GENET, V96, P384, DOI 10.1002/1096-8628(20000612)96:3<384::AID-AJMG28>3.0.CO

[8]

2-P

[9] Decision-making heterogeneity in obsessive-compulsive disorder: Ventromedial prefrontal cortex function predicts different treatment outcomes [J].

Cavedini, P ;

Riboldi, G ;

D'Annucci, A ;

Belotti, P ;

Cisima, M ;

Bellodi, L .

NEUROPSYCHOLOGIA, 2002, 40 (02) :205-211

[10] Neuropsychological investigation of decision-making in anorexia nervosa [J].

Cavedini, P ;

Bassi, T ;

Ubbiali, A ;

Casolari, A ;

Giordani, S ;

Zorzi, C ;

Bellodi, L .

PSYCHIATRY RESEARCH, 2004, 127 (03) :259-266

← 1 2 3 →