Proteins that bind to double-stranded regions of telomeric DNA

被引:51
作者
Brun, C
Marcand, S
Gilson, E
机构
[1] Laboratoire de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique, Ecole Normale Supérieure de Lyon, 69364 Lyon Cedex 07
关键词
D O I
10.1016/S0962-8924(97)01092-1
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
In budding yeast, the DNA-binding protein Rap1p orchestrates a negative feedback on regulation of telomere length and the organization of a heterochromatin-like telomeric compartment. Recent studies have led to the identification of functionally related telomeric proteins from fission yeast and mammals. These advances underline the key role played by the proteins that bind to the duplex part of telomeric DNA and reveal an important structural diversity among telomeric proteins.
引用
收藏
页码:317 / 324
页数:8
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