Natural killer T cells and CD8+ T cells are dispensable for T cell-dependent allergic airway inflammation

被引：45

作者：

Das, Jyoti

Eynott, Paul

Jupp, Ray

Bothwell, Alfred

Van Kaer, Luc

Shi, Yufang

Das, Gobardhan

机构：

[1] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Dept Mol Genet Microbiol & Immunol, Piscataway, NJ 08854 USA

[2] Sanofi Aventis, Div Internal Med, Bridgewater, NJ 08807 USA

[3] Yale Univ, Sch Med, Immunobiol Sect, New Haven, CT 06510 USA

[4] Vanderbilt Univ, Dept Microbiol & Immunol, Nashville, TN 37232 USA

来源：

NATURE MEDICINE | 2006年 / 12卷 / 12期

关键词：

D O I：

10.1038/nm1206-1345

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1345 / 1346

页数：2

共 10 条

[1] Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity [J].

Akbari, O ;

Stock, P ;

Meyer, E ;

Kronenberg, M ;

Sidobre, S ;

Nakayama, T ;

Taniguchi, M ;

Grusby, MJ ;

DeKruyff, RH ;

Umetsu, DT .

NATURE MEDICINE, 2003, 9 (05) :582-588

[2] A critical role for NF-κB in Gata3 expression and TH2 differentiation in allergic airway inflammation [J].

Das, J ;

Chen, CH ;

Yang, LY ;

Cohn, L ;

Ray, P ;

Ray, A .

NATURE IMMUNOLOGY, 2001, 2 (01) :45-50

[3] Resident CD8+ T cells suppress CD4+ T cell-dependent late allergic airway responses [J].

Isogai, S ;

Jedrzkiewicz, S ;

Taha, R ;

Hamid, Q ;

Martin, JG .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2005, 115 (03) :521-526

[4] Complex role of the IL-4 receptor α in a murine model of airway inflammation:: expression of the IL-4 receptor α on nonlymphoid cells of bone marrow origin contributes to severity of inflammation [J].

Kelly-Welch, AE ;

Melo, MEF ;

Smith, E ;

Ford, AQ ;

Haudenschild, C ;

Noben-Trauth, N ;

Keegan, AD .

JOURNAL OF IMMUNOLOGY, 2004, 172 (07) :4545-4555

[5] PHENOTYPIC CHARACTERIZATION OF T-LYMPHOCYTES EMIGRATING INTO LUNG-TISSUE AND THE AIRWAY LUMEN AFTER ANTIGEN INHALATION IN SENSITIZED MICE [J].

KENNEDY, JD ;

HATFIELD, CA ;

FIDLER, SF ;

WINTERROWD, GE ;

HAAS, JV ;

CHIN, JE ;

RICHARDS, IM .

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 1995, 12 (06) :613-623

[6] Natural killer cells determine development of allergen-induced eosinophilic airway inflammation in mice [J].

Korsgren, M ;

Persson, CGA ;

Sundler, F ;

Bjerke, T ;

Hansson, T ;

Chambers, BJ ;

Hong, SM ;

Van Kaer, L ;

Ljunggren, HG ;

Korsgren, O .

JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 189 (03) :553-562

[7] Effector CD8+ T cells mediate inflammation and airway hyper-responsiveness [J].

Miyahara, N ;

Swanson, BJ ;

Takeda, K ;

Taube, C ;

Miyahara, S ;

Kodama, T ;

Dakhama, A ;

Ott, VL ;

Gelfand, EW .

NATURE MEDICINE, 2004, 10 (08) :865-869

[8] Changes in sputum T-lymphocyte subpopulations at the onset of severe exacerbations of chronic obstructive pulmonary disease [J].

Tsoumakidou, M ;

Tzanakis, N ;

Chrysofakis, G ;

Kyriakou, D ;

Siafakas, NM .

RESPIRATORY MEDICINE, 2005, 99 (05) :572-579

[9] Positive selection of MHC class Ib-restricted CD8+ T cells on hematopoietic cells [J].

Urdahl, KB ;

Sun, JC ;

Bevan, MJ .

NATURE IMMUNOLOGY, 2002, 3 (08) :772-779

[10] beta 2-microglobulin-dependent T cells are dispensable for allergen-induced T helper 2 responses [J].

Zhang, Y ;

Rogers, KH ;

Lewis, DB .

JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 184 (04) :1507-1512

← 1 →