Adverse effect of TNF-alpha blocker? Demyelination in an ankylosing spondylitis patient: a case report

被引：15

作者：

Cay, H. F. ^{[1
]}

Gungor, H. A.

Sezer, I.

Kacar, C.

Balci, N.

机构：

[1] Akdeniz Univ, Fac Med, Phys Med Rehabil & Rheumatol Dept, Antalya, Turkey

[2] Akdeniz Univ, Fac Med, Dept Neurol, Antalya, Turkey

来源：

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS | 2006年 / 31卷 / 06期

关键词：

ankylosing spondylitis; anti-tumour necrosis factor-alpha drugs; transverse myelitis;

D O I：

10.1111/j.1365-2710.2006.00779.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Anti-tumour necrosis factor (TNF)-alpha agents promise better disease control for treatment of inflammatory arthritides which are resistant to classical disease-modifying treatment and provide better functional outcome. But these agents are not free of adverse events. The exact relationship between use of anti-TNF drugs and development of demyelination cannot be established yet. Here we present a case of a 36-year-old man who developed demyelination in the cervical spinal cord while he was being treated with etanercept for ankylosing spondylitis.

引用

页码：645 / 648

页数：4

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