Stereoselective synthesis of D-erythro- and L-threo-sphinganines via palladium-catalyzed equilibration and Suzuki coupling

被引：25

作者：

Cook, GR ^{[1
]}

Pararajasingham, K ^{[1
]}

机构：

[1] N Dakota State Univ, Dept Chem, Fargo, ND 58105 USA

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 50期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0040-4039(02)02309-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Pd-catalyzed isomerization of 5-vinyloxazolines was utilized for the stereoselective synthesis of D-erythro- and L-threo-spinganine triacetate. A hydroboration/Suzuki coupling sequence was employed to elongate the hydrophobic chain. (C) 2002 Elsevier Science Ltd. All rights reserved.

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页码：9027 / 9029

页数：3

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