The pharmacologic mechanism by which inhaled epinephrine reduces airway obstruction in respiratory syncytial virus-associated bronchiolitis

被引：22

作者：

Barr, FE

Patel, NR

Newth, CJL

机构：

[1] Vanderbilt Univ, Ctr Med, Vanderbilt Childrens Hosp, Div Pediat Crit Care & Anesthesia, Nashville, TN 37232 USA

[2] Univ So Calif, Childrens Hosp Los Angeles, Div Pediat Crit Care, Los Angeles, CA USA

来源：

JOURNAL OF PEDIATRICS | 2000年 / 136卷 / 05期

关键词：

D O I：

10.1067/mpd.2000.105358

中图分类号：

R72 [儿科学];

学科分类号：

100202 [儿科学];

摘要：

Inhaled racemic epinephrine relieves airway obstruction in patients with respiratory syncytial virus bronchiolitis. The contribution of alpha- versus beta- adrenoreceptor stimulation toward this clinical effect is unknown. We describe an infant treated with propranolol for supraventricular tachycardia in whom respiratory syncytial virus bronchiolitis developed. Inhaled racemic epinephrine improved his respiratory symptoms, whereas nebulized albuterol did not.

引用

页码：699 / 700

页数：2

共 9 条

[1]

ALBUTEROL RESPONSIVENESS IN INFANTS WITH RESPIRATORY-FAILURE CAUSED BY RESPIRATORY SYNCYTIAL VIRUS-INFECTION [J].

HAMMER, J ;

NUMA, A ;

NEWTH, CJL .

JOURNAL OF PEDIATRICS, 1995, 127 (03) :485-490

[2]

NEBULIZED RACEMIC ADRENALINE IN THE TREATMENT OF ACUTE BRONCHIOLITIS IN INFANTS AND TODDLERS [J].

KRISTJANSSON, S ;

CARLSEN, KCL ;

WENNERGREN, G ;

STRANNEGARD, IL ;

CARLSEN, KH .

ARCHIVES OF DISEASE IN CHILDHOOD, 1993, 69 (06) :650-654

[3]

ALPHA AND BETA-ADRENERGIC STIMULANTS IN BRONCHIOLITIS AND WHEEZY BRONCHITIS IN CHILDREN UNDER 18 MONTHS OF AGE [J].

LENNEY, W ;

MILNER, AD .

ARCHIVES OF DISEASE IN CHILDHOOD, 1978, 53 (09) :707-709

[4]

A RANDOMIZED TRIAL COMPARING THE EFFICACY OF EPINEPHRINE WITH SALBUTAMOL IN THE TREATMENT OF ACUTE BRONCHIOLITIS [J].

MENON, K ;

SUTCLIFFE, T ;

KLASSEN, TP .

JOURNAL OF PEDIATRICS, 1995, 126 (06) :1004-1007

[5]

The effects of bronchodilators on spontaneous ventilation and oxygen consumption in rhesus monkeys [J].

Newth, CJL ;

Amsler, B ;

Richardson, BP ;

Hammer, J .

PEDIATRIC RESEARCH, 1997, 42 (02) :157-162

[6]

PROPRANOLOL TREATMENT OF ALBUTEROL POISONING IN 2 ASTHMATIC-PATIENTS [J].

RAMOSKA, EA ;

HENRETIG, F ;

JOFFE, M ;

SPILLER, HA .

ANNALS OF EMERGENCY MEDICINE, 1993, 22 (09) :1474-1476

[7]

THE CLINICAL EFFICACY OF NEBULIZED RACEMIC EPINEPHRINE AND ALBUTEROL IN ACUTE BRONCHIOLITIS [J].

REIJONEN, T ;

KORPPI, M ;

PITKAKANGAS, S ;

TENHOLA, S ;

REMES, K .

ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE, 1995, 149 (06) :686-692

[8]

EFFECT OF RACEMIC EPINEPHRINE AND SALBUTAMOL ON CLINICAL SCORE AND PULMONARY MECHANICS IN INFANTS WITH BRONCHIOLITIS [J].

SANCHEZ, I ;

DEKOSTER, J ;

POWELL, RE ;

WOLSTEIN, R ;

CHERNICK, V .

JOURNAL OF PEDIATRICS, 1993, 122 (01) :145-151

[9]

CLINICAL SCORING SYSTEM FOR DIAGNOSIS OF RESPIRATORY FAILURE - PRELIMINARY REPORT ON CHILDHOOD STATUS ASTHMATICUS [J].

WOOD, DW ;

DOWNES, JJ ;

LECKS, HI .

AMERICAN JOURNAL OF DISEASES OF CHILDREN, 1972, 123 (03) :227-&

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