Clinical and macroscopic correlates of minicolumnar pathology in autism

被引：122

作者：

Casanova, MF

Buxhoeveden, DP

Brown, C

机构：

[1] Med Coll Georgia, Dept Psychiat, Augusta, GA 30912 USA

[2] Med Coll Georgia, Dept Neurol, Augusta, GA 30912 USA

[3] Med Coll Georgia, Dept Anat, Augusta, GA 30912 USA

[4] Univ Bristol, Dept Expt Psychol, Bristol BS8 1TH, Avon, England

来源：

JOURNAL OF CHILD NEUROLOGY | 2002年 / 17卷 / 09期

关键词：

D O I：

10.1177/088307380201700908

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

All subcortical arrangements are primarily nuclear in type. The cortex has been the first part of the brain to evolve a radial and laminar arrangement of cells. The resultant modular arrangement is based on the cell minicolumn: a self-contained ecosystem of connectivity linking afferent, efferent, and inerneuronal connections. Recently, the cell minicolumn has been found to be abnormal in patients with autism. This article relates different aspects of the cell minicolumn and larger-scale neuronal assemblies to potential research techniques and their application to clinical practice.

引用

页码：692 / 695

页数：4

共 61 条

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