The effect of thymol and its derivatives on reactions generating reactive oxygen species

被引：127

作者：

Kruk, I

Michalska, T

Lichszteld, K

Kladna, A

Aboul-Enein, HY

机构：

[1] Tech Univ Szczecin, Inst Phys, PL-70311 Szczecin, Poland

[2] Univ Szczecin, Fac Nat Sci, Dept Human Ecol, PL-71065 Szczecin, Poland

[3] King Faisal Specialist Hosp & Res Ctr, Dept Biol & Med Res, Bioanalyt & Drug Dev Lab, Riyadh 11211, Saudi Arabia

来源：

CHEMOSPHERE | 2000年 / 41卷 / 07期

关键词：

thymol; thymoquinone; dithymoquinone; oxygen free radicals; singlet oxygen;

D O I：

10.1016/S0045-6535(99)00454-3

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 [工学]; 0830 [环境科学与工程];

摘要：

The effects of thymol (TOH), thymoquinone (TQ) and dithymoquinone (TQ?) on the reactions generating reactive oxygen species (ROS) such as superoxide anion radical (O-2(.-)), hydroxyl radical (HO.) and singlet oxygen (O-1(2)) were tested using the chemiluminescence (CL) and spectrophotometry methods. All tested compounds acted as scavengers of various ROS. The rate constant of O-1(2)-dimols quenching by thymol was calculated. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：1059 / 1064

页数：6

共 22 条

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[2]

Aboutabl E.A., 1986, Progress in Essential Oil Research, V16, P49

[3]

Thymoquinone ameliorates the nephrotoxicity induced by cisplatin in rodents and potentiates its antitumor activity [J].