Blood glucose level on postoperative day 1 is predictive of adverse outcomes after cardiovascular surgery

被引:14
作者
Frioud, A. [1 ]
Comte-Perret, S. [1 ]
Nguyen, S. [1 ]
Berger, M. M. [2 ]
Ruchat, P. [3 ]
Ruiz, J. [1 ]
机构
[1] CHU Vaudois, Dept Diabet Endocrinol & Metab, CH-1011 Lausanne, Switzerland
[2] CHU Vaudois, Dept Adult Intens Care, CH-1011 Lausanne, Switzerland
[3] CHU Vaudois, Dept Cardiovasc Surg, CH-1011 Lausanne, Switzerland
关键词
Diabetes; Hyperglycaemia; Hypoglycaemia; Mortality; Coronary artery bypass Grafting; Surgery; Post-surgery monitoring; INTENSIVE INSULIN THERAPY; CRITICALLY-ILL PATIENTS; PERIOPERATIVE GLYCEMIC CONTROL; DIABETIC-PATIENTS; INFECTIOUS COMPLICATIONS; CAROTID-ENDARTERECTOMY; WOUND-INFECTION; BYPASS SURGERY; CORONARY; MORTALITY;
D O I
10.1016/j.diabet.2009.06.008
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aim. - Hyperglycaemia is now it recognized predictive factor of morbidity and mortality after corollary artery bypass grafting (CABG). For this reason, We aimed to evaluate the Postoperative management of glucose control ill patients undergoing cardiovascular surgery, and to assess the impact of glucose level,, on in-hospital mortality and morbidity. Methods. - This was it retrospective study investigating the association between post operative blood glucose and outcomes, including death, post-surgical complications, and length of stay in the intensive Care Unit (ICU) and in hospital. Results. - A total of 642 consecutive patients were enrolled into the study after cardiovascular surgery (CABG, carotid endarterectomy and bypass in the lower limbs). Patients' mean age was 68 10 years, and 74% were male. In-hospital mortality was 5% in diabetic patients vs 2% ill non-diabetic patients (OR: 1.66 P=0.076). Having, blood glucose levels ill the upper quartile range (>= 8.8 mmol/L) oil postoperative day I was independent]), associated with death (OR: 10. 16 P = 0.0002), infections complications (OR: 1.76 P = 0.04) and prolonged ICU stay (OR: 3. 10, P < 0.0001 patients presenting with till-cc of more hypoglycaemic episodes (< 4.1 mmol/L) had increased rates of mortality (OR: 9.08, P < 0.000 1 and complications (OR: 8.57. P<0.0001). Conclusion. - Glucose levels greater than 8.8 mmol/L oil postoperative day I and having three or more hypoglycaemic episodes in the postoperative period were predictive of mortality and morbidity among patient. undergoing cardiovascular surgery. This suggests that it Multidisciplinary approach may be able to achieve better postoperative blood glucose Control. (C) 2009 Published by Elsevier Masson SAS.
引用
收藏
页码:36 / 42
页数:7
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