Regulation of T cell function by NK cell receptors for classical MHC class I molecules

被引：63

作者：

Ugolini, S ^{[1
]}

Vivier, E ^{[1
]}

机构：

[1] CNRS, INSERM, Ctr Immunol Marseille Luminy, Campus Univ Luminy,Case 906, F-13288 Marseille 09, France

来源：

CURRENT OPINION IN IMMUNOLOGY | 2000年 / 12卷 / 03期

关键词：

D O I：

10.1016/S0952-7915(00)00090-X

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Inhibitory receptors for MHC class I molecules were initially characterised on NK cells. Human and mouse NK cell receptors (NKRs) are also expressed on T cells, predominantly on a subset of memory-phenotype CD8(+) T cells. This review focuses on the precise determination of interactions between NKRs and MHC class I, as well as on the unexpected in vivo function of NKRs on T cells.

引用

页码：295 / 300

页数：6

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