Brine shrimp lethality bioassay of selected Indian medicinal plants

被引:56
作者
Padmaja, R
Arun, PC
Prashanth, D
Deepak, M
Amit, A
Anjana, M
机构
[1] Nat Remedies Pvt Ltd, Ctr Res & Dev, Bioassay Unit, Bangalore 561229, Karnataka, India
[2] Nat Remedies Pvt Ltd, Ctr Res & Dev, Phytochem Lab, Bangalore 561229, Karnataka, India
关键词
brine shrimp lethality test; Acorus calamus; Centella asiatica; Centratherum anthelminticum; Mangifera indica; Commiphora mukul; Piper longum; guggulsterone E; guggulsterone Z; piperine;
D O I
10.1016/S0367-326X(02)00182-X
中图分类号
R914 [药物化学];
学科分类号
100701 [药物化学];
摘要
Ethanolic extracts of six Indian medicinal plants, piperine, guggulsterone E and guggulsterone Z were tested for cytotoxicity using brine shrimp lethality test. Piper longum showed most potent cytotoxic activity. Piperine, guggulsterone E and guggulsterone Z showed potent activity with LC50 2.4, 8.9 and 4.9, respectively. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:508 / 510
页数:3
相关论文
共 9 条
[1]
ARORA RB, 1971, INDIAN J EXP BIOL, V9, P403
[2]
HUSAIN A, 1992, DICT INDIAN MED PLAN
[3]
KOKATE CK, 1996, PHARMACOGNOSY, P123
[4]
NADKARNI AK, 1993, INDIAN MAT MED, V1
[5]
NITYANAND S, 1973, INDIAN J EXP BIOL, V11, P395
[6]
Sam Teng Wah, 1993, P441
[7]
SATYAVATHI GK, 1987, MED PLANTS INDIA, V2
[8]
TREASE EG, 1989, TXB PHARMACOGNOSY, P546
[9]
Wagner H., 1996, PLANT DRUG ANAL