Composition and biological activity of the essential oil from leaves of Plinia cerrocampanensis, a new source of α-bisabolol

被引:70
作者
Vila, Roser [1 ]
Isabel Santana, Ana [2 ]
Perez-Roses, Renato [1 ]
Valderrama, Anayansi
Victoria Castelli, M. [3 ]
Mendonca, Sergio [4 ]
Zacchino, Susana [3 ]
Gupta, Mahabir P. [2 ]
Canigueral, Salvador [1 ]
机构
[1] Univ Barcelona, Fac Farm, Unitat Farmacol & Farmacognosia, E-08028 Barcelona, Spain
[2] Univ Panama, Fac Farm, Ctr Invest Farmacognost Flora Panamena CIFLORPAN, Panama City, Panama
[3] Univ Nacl Rosario, Lab Farmacognosia, Fac Ciencias Bioquim & Farmaceut, RA-2000 Rosario, Argentina
[4] Univ Bandeirante Sao Paulo, Microbiol Lab, Sao Paulo, Brazil
关键词
Plinia cerrocampanensis; Essential oil; alpha-Bisabolol; Antimicrobial activity; Aedes aegypti; ANTIMICROBIAL ACTIVITY; LARVICIDAL ACTIVITY; CONSTITUENTS; (-)-LINALOOL; INVOLVEMENT; COMPONENTS; CHAMOMILE; NEROLIDOL; LINALOOL; URB;
D O I
10.1016/j.biortech.2009.11.021
中图分类号
S2 [农业工程];
学科分类号
082806 [农业信息与电气工程];
摘要
The essential oil from fresh leaves of Plinia cerrocampanensis Barrie (Myrtaceae), obtained by hydrodistillation, was analysed by CC-FID and GC-MS. Forty components, representing more than 91% of the oil, were identified. Oxygenated sesquiterpenes represented the main fraction with a-bisabolol (42.8%) as the major constituent, making this plant a new and good source of this substance. Biological activity of the essential oil was evaluated against several bacterial and fungal strains as well as larvae from Aedes aegypti. The highest activity was found against Staphylococcus aureus, Pseudomonas aeruginosa, Microsporum gypseum, Trichophyton mentagrophytes and Trichophyton rubrum with MIC values from 32 to 125 mu g/ml. The essential oil also showed potent inhibitory and bactericidal activities against three H. pylori strains, with MIC and MBC values of 62.5 mu g/ml, and caused 100% mortality of A. aegypti larvae at a concentration of 500 mu g/ml. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2510 / 2514
页数:5
相关论文
共 37 条
[1]
Adams R.P., 2004, Identification of Essential Oil Components by Gas Chromatography/Quadrupole Mass Spectroscopy
[2]
Essential oil composition of four Plinia species (Myrtaceae) [J].
Apel, Miriam A. ;
Sobral, Marcos ;
Zuanazzi, Josl Angelo ;
Henriques, Amelia T. .
FLAVOUR AND FRAGRANCE JOURNAL, 2006, 21 (03) :565-567
[3]
Biological effects of essential oils - A review [J].
Bakkali, F. ;
Averbeck, S. ;
Averbeck, D. ;
Waomar, M. .
FOOD AND CHEMICAL TOXICOLOGY, 2008, 46 (02) :446-475
[4]
Barrie FR, 2004, NOVON, V14, P380
[5]
Sensitization of Staphylococcus aureus and Escherichi coli to antibiotics by the sesquiterpenoid nerolidol, farnesol, bisabolol, and apritone [J].
Brehm-Stecher, BF ;
Johnson, EA .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (10) :3357-3360
[6]
Carson Christine F, 2003, Commun Dis Intell Q Rep, V27 Suppl, pS143
[7]
Larvicidal activity of the essential oil from Lippia sidoides Cham. against Aedes aegypti Linn. [J].
Carvalho, AFU ;
Melo, VMM ;
Craveiro, AA ;
Machado, MIL ;
Bantim, MB ;
Rabelo, EF .
MEMORIAS DO INSTITUTO OSWALDO CRUZ, 2003, 98 (04) :569-571
[8]
Larvicidal activity of essential oils from Brazilian plants against Aedes aegypti L. [J].
Cavalcanti, ESB ;
de Morais, SM ;
Lima, MAA ;
Santana, EWP .
MEMORIAS DO INSTITUTO OSWALDO CRUZ, 2004, 99 (05) :541-544
[9]
α-bisabolol, a nontoxic natural compound, strongly induces apoptosis in glioma cells [J].
Cavalieri, E ;
Mariotto, S ;
Fabrizi, C ;
de Prati, AC ;
Gottardo, R ;
Leone, S ;
Berra, LV ;
Lauro, GM ;
Ciampa, AR ;
Suzuki, H .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2004, 315 (03) :589-594
[10]
Chemical compositions and larvicidal activities of leaf essential oils from two eucalyptus species [J].
Cheng, Sen-Sung ;
Huang, Chin-Gi ;
Chen, Ying-Ju ;
Yu, Jane-Jane ;
Chen, Wei-June ;
Chang, Shang-Tzen .
BIORESOURCE TECHNOLOGY, 2009, 100 (01) :452-456