Functional activation in motor cortex reflects the direction and the degree of handedness

被引:235
作者
Dassonville, P
Zhu, XH
Ugurbil, K
Kim, SG
Ashe, J
机构
[1] VET AFFAIRS MED CTR, BRAIN SCI CTR, MINNEAPOLIS, MN 55417 USA
[2] UNIV MINNESOTA, DEPT NEUROL, MINNEAPOLIS, MN 55455 USA
[3] UNIV MINNESOTA, DEPT RADIOL, MINNEAPOLIS, MN 55455 USA
[4] UNIV MINNESOTA, CTR MAGNET RESONANCE RES, MINNEAPOLIS, MN 55455 USA
关键词
D O I
10.1073/pnas.94.25.14015
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Handedness is the dearest example of behavioral lateralization in humans. It is not known whether the obvious asymmetry manifested by hand preference is associated with similar asymmetry in brain activation during movement. We examined the functional activation in cortical motor areas during movement of the dominant and nondominant hand in groups of right-handed and left-handed subjects and found that use of the dominant hand was associated with a greater volume of activation in the contralateral motor cortex. Furthermore, there was a separate relation between the degree of handedness and the extent of functional lateralization in the motor cortex. The patterns of functional activation associated with the direction and degree of handedness suggest that these aspects are independent and are coded separately in the brain.
引用
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页码:14015 / 14018
页数:4
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