Archaea analogue thiolipids for tethered bilayer lipid membranes on ultrasmooth gold surfaces

被引：232

作者：

Schiller, SM

Naumann, R

Lovejoy, K

Kunz, H

Knoll, W

机构：

[1] Max Planck Inst Polymer Res, D-55128 Mainz, Germany

[2] Northwestern Univ, Dept Chem, Evanston, IL 60208 USA

[3] Univ Mainz, Inst Organ Chem, D-55128 Mainz, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 02期

关键词：

gold; lipids; membranes; monolayers; self-assembly;

D O I：

10.1002/anie.200390080

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Simple vesicle fusion allowed the formation of a bilayer lipid membrane from the self-assembled monolayer of lipoic acid ester 1 (see formula). Film thicknesses determined by surface plasmon resonance (SPR) spectroscopic measurements agree with the theoretical thicknesses of the stretched conformation. Electrochemical impedance spectroscopy (EIS) of the model system shows that the latter exhibits similar electrical properties to biological membranes.

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页码：208 / +

页数：5

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