Cellular bases of a vertebrate locomotor system -: steering, intersegmental and segmental co-ordination and sensory control

被引:116
作者
Grillner, S [1 ]
Wallén, P [1 ]
机构
[1] Karolinska Inst, Nobel Inst Neurophysiol, Dept Neurosci, Retzius Lab, SE-17177 Stockholm, Sweden
关键词
lamprey; locomotion; neuronal network; steering; ion channels; sensory control;
D O I
10.1016/S0165-0173(02)00193-5
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The isolated brainstem-spinal cord of the lamprey is used as an experimental model in the analysis of the cellular bases of vertebrate locomotor behaviour. In this article we review the neural mechanisms involved in the control of steering, intersegmental co-ordination, as well as the segmental burst generation and the sensory contribution to motor pattern generation. Within these four components of the control system for locomotion, we now have good knowledge of not only the neurones that take part and their synaptic interactions, but also the membrane properties of these neurones, including ion channel subtypes, and their contribution to motor pattern generation. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:92 / 106
页数:15
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