Personalized Medicine and Inhibition of EGFR Signaling in Lung Cancer.

被引:148
作者
Gazdar, Adi F. [1 ,2 ]
机构
[1] Simmons Canc Ctr, Hamon Ctr Therapeut Oncol Res, Dallas, TX USA
[2] Univ Texas SW Med Ctr Dallas, Dept Pathol, Dallas, TX 75390 USA
关键词
GROWTH-FACTOR RECEPTOR; THERAPY;
D O I
10.1056/NEJMe0905763
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1018 / 1020
页数:3
相关论文
共 10 条
  • [1] Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients
    Cappuzzo, F
    Varella-Garcia, M
    Shigematsu, H
    Domenichini, I
    Bartolini, S
    Ceresoli, GL
    Rossi, E
    Ludovini, V
    Gregorc, V
    Toschi, L
    Franklin, WA
    Crino, L
    Gazdar, AF
    Bunn, RA
    Hirsch, FR
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (22) : 5007 - 5018
  • [2] The epidermal growth factor receptor: A role in repair of radiation-induced DNA damage
    Chen, David J.
    Nirodi, Chaitanya S.
    [J]. CLINICAL CANCER RESEARCH, 2007, 13 (22) : 6555 - 6560
  • [3] Alterations in Genes of the EGFR Signaling Pathway and Their Relationship to EGFR Tyrosine Kinase Inhibitor Sensitivity in Lung Cancer Cell Lines
    Gandhi, Jeet
    Zhang, Jianling
    Xie, Yang
    Soh, Junichi
    Shigematsu, Hisayuki
    Zhang, Wei
    Yamamoto, Hiromasa
    Peyton, Michael
    Girard, Luc
    Lockwood, William W.
    Lam, Wan L.
    Varella-Garcia, Marileila
    Minna, John D.
    Gazdar, Adi F.
    [J]. PLOS ONE, 2009, 4 (02):
  • [4] The hallmarks of cancer
    Hanahan, D
    Weinberg, RA
    [J]. CELL, 2000, 100 (01) : 57 - 70
  • [5] Gefitinib or Carboplatin-Paclitaxel in Pulmonary Adenocarcinoma.
    Mok, Tony S.
    Wu, Yi-Long
    Thongprasert, Sumitra
    Yang, Chih-Hsin
    Chu, Da-Tong
    Saijo, Nagahiro
    Sunpaweravong, Patrapim
    Han, Baohui
    Margono, Benjamin
    Ichinose, Yukito
    Nishiwaki, Yutaka
    Ohe, Yuichiro
    Yang, Jin-Ji
    Chewaskulyong, Busyamas
    Jiang, Haiyi
    Duffield, Emma L.
    Watkins, Claire L.
    Armour, Alison A.
    Fukuoka, Masahiro
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (10) : 947 - 957
  • [6] Screening for Epidermal Growth Factor Receptor Mutations in Lung Cancer.
    Rosell, Rafael
    Moran, Teresa
    Queralt, Cristina
    Porta, Rut
    Cardenal, Felipe
    Camps, Carlos
    Majem, Margarita
    Lopez-Vivanco, Guillermo
    Isla, Dolores
    Provencio, Mariano
    Insa, Amelia
    Massuti, Bartomeu
    Luis Gonzalez-Larriba, Jose
    Paz-Ares, Luis
    Bover, Isabel
    Garcia-Campelo, Rosario
    Angel Moreno, Miguel
    Catot, Silvia
    Rolfo, Christian
    Reguart, Noemi
    Palmero, Ramon
    Miguel Sanchez, Jose
    Bastus, Roman
    Mayo, Clara
    Bertran-Alamillo, Jordi
    Angel Molina, Miguel
    Javier Sanchez, Jose
    Taron, Miquel
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (10) : 958 - U38
  • [7] Toward Noninvasive Genomic Screening of Lung Cancer Patients
    Sequist, Lecia V.
    Engelman, Jeffrey A.
    Lynch, Thomas J.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (16) : 2589 - 2591
  • [8] Epidermal growth factor receptor mutations in lung cancer
    Sharma, Sreenath V.
    Bell, Daphne W.
    Settleman, Jeffrey
    Haber, Daniel A.
    [J]. NATURE REVIEWS CANCER, 2007, 7 (03) : 169 - 181
  • [9] Unraveling the mystery of prognostic and predictive factors in epidermal growth factor receptor therapy
    Shepherd, FA
    Tsao, MS
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (07) : 1219 - 1220
  • [10] Erlotinib in previously treated non-small-cell lung cancer
    Shepherd, FA
    Pereira, JR
    Ciuleanu, T
    Tan, EH
    Hirsh, V
    Thongprasert, S
    Campos, D
    Maoleekoonpiroj, S
    Smylie, M
    Martins, R
    van Kooten, M
    Dediu, M
    Findlay, B
    Tu, DS
    Johnston, D
    Bezjak, A
    Clark, G
    Santabárbara, P
    Seymour, L
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (02) : 123 - 132