Getting into the fold

被引：6

作者：

Brooks, Doug A.

机构：

[1] Univ S Australia, Mol Med Sector, Sansom Inst, Adelaide, SA 5001, Australia

[2] Womens & Childrens Hosp, Lysosomal Dis Res Unit, Adelaide, SA 5006, Australia

来源：

NATURE CHEMICAL BIOLOGY | 2007年 / 3卷 / 02期

关键词：

D O I：

10.1038/nchembio0207-84

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Pharmacological chaperones are small molecules that interact with a protein to enhance folding and stability. Understanding the chemistry underlying the interaction of pharmacological chaperones with their target proteins will facilitate the design of more efficient drugs with greater therapeutic potential.

引用

收藏

页码：84 / 85

页数：3

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