Dysphagia in Crohn's disease: a diagnostic challenge

被引:10
作者
Knoblauch, C [1 ]
Netzer, P [1 ]
Scheurer, U [1 ]
Seibold, F [1 ]
机构
[1] Univ Bern, Inselspital, Dept Gastroenterol, Unit Gl, CH-3010 Bern, Switzerland
关键词
achalasia; Crohn's disease; dysphagia; oesophageal fistula;
D O I
10.1016/S1590-8658(02)80210-9
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Dysphagia is a rare manifestation in a patient with Crohns disease. We report on the case of a patient with long-standing Crohns disease who developed progressive dysphagia over 3 years. Endoscopy showed minimal distal oesophagitis with non-specific histological findings. Further investigation with cinematography, barium swallow and manometry established an achalasia-like motility disorder. Biopsies obtained from the oesophagus were non-specific. Balloon dilatation was performed. Initial success was followed by recurrent dysphagia. At repeat endoscopy an oesophageal fistula was detected. An attempt at conservative medical management failed and oesophagectomy was successfully performed. Pathology results of the resected specimen confirmed the suspected diagnosis of oesophageal Crohn's disease. Even if achalasia is suspected in a Crohn's patient, it should be taken into consideration that the motility disorder could be the result of a transmural inflammation with or without fibrosis caused by Crohn's disease.
引用
收藏
页码:660 / 664
页数:5
相关论文
共 24 条
[1]
IDIOPATHIC ULCERATIVE ESOPHAGITIS - REPORT OF A CASE [J].
ACHENBACH, H ;
LYNCH, JP ;
DWIGHT, RW .
NEW ENGLAND JOURNAL OF MEDICINE, 1956, 255 (10) :456-459
[2]
Esophageal motility disorders and strictures [J].
Allescher, HD .
ENDOSCOPY, 2000, 32 (11) :850-852
[3]
Gastrointestinal motility disorders in patients with inactive Crohn's disease [J].
Annese, V ;
Bassotti, G ;
Napolitano, G ;
Usai, P ;
Andriulli, A ;
Vantrappen, G .
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 1997, 32 (11) :1107-1117
[4]
A 34-YEAR-OLD WOMAN WITH PERSISTENT COUGH AND DIARRHEA [J].
BRITTON, CA ;
JARMOLOWSKI, CR ;
WINZELBERG, GG .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1986, 255 (20) :2785-2787
[5]
Esophageal Crohn's disease with esophagopleural fistula [J].
Cosme, A ;
Bujanda, L ;
Arriola, JA ;
Ojeda, E .
ENDOSCOPY, 1998, 30 (09) :S109-S109
[6]
CROHNS-DISEASE OF ESOPHAGUS [J].
CYNN, W ;
CHON, H ;
GUREGHIAN, PA ;
LEVIN, BL .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1975, 125 (02) :359-364
[7]
DAVIDSON JT, 1983, AM SURGEON, V49, P168
[8]
BARRETTS MUCOSA OF DISTAL ESOPHAGUS WITH CONCOMITANT ISOLATED CROHNS-DISEASE AND INTRAMUCOSAL ADENOCARCINOMA - REPORT OF A CASE AND ANALYSIS OF THE LITERATURE [J].
DELPRE, G ;
MOR, C ;
AVIDOR, I ;
GUTMAN, H ;
LEISSER, A ;
KOTT, I ;
KADISH, U .
DIGESTIVE DISEASES AND SCIENCES, 1989, 34 (02) :304-311
[9]
DEVARANNES SB, 2001, DIGEST LIVER DIS, V33, P266
[10]
FRANKLIN RH, 1950, J THORAC SURG, V19, P292