Mitochondria as we don't know them

被引:223
作者
Tielens, AGM
Rotte, C
van Hellemond, JJ
Martin, W
机构
[1] Univ Utrecht, Dept Biochem & Cell Biol, Fac Med Vet, NL-3508 TD Utrecht, Netherlands
[2] Univ Dusseldorf, Inst Bot 3, D-40225 Dusseldorf, Germany
关键词
D O I
10.1016/S0968-0004(02)02193-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Biochemistry textbooks depict mitochondria as oxygen-dependent organelles, but many mitochondria can produce ATP without using any oxygen. In fact, several other types of mitochondria exist and they occur in highly diverse groups of eukaryotes-protists as well as metazoans-and possess an often overlooked diversity of pathways to deal with the electrons resulting from carbohydrate oxidation. These anaerobically functioning mitochondria produce ATP with the help of proton-pumping electron transport, but they do not need oxygen to do so. Recent advances in understanding of mitochondrial biochemistry provide many surprises and furthermore, give insights into the evolutionary history of ATP-producing organelles.
引用
收藏
页码:564 / 572
页数:9
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