The effect of divided attention on encoding and retrieval in episodic memory revealed by positron emission tomography

被引:113
作者
Iidaka, T
Anderson, ND
Kapur, S
Cabeza, R
Craik, FIM
机构
[1] Fukui Med Univ, Biomed Imaging Res Ctr, Fukui 9101193, Japan
[2] Univ Toronto, Toronto, ON, Canada
[3] Princess Margaret Hosp, Toronto, ON M4X 1K9, Canada
[4] Univ Alberta, Edmonton, AB T6G 2M7, Canada
关键词
D O I
10.1162/089892900562093
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The effects of divided attention (DA) on episodic memory encoding and retrieval were investigated in 12 normal young subjects by positron emission tomography (PET). Cerebral blood flow was measured while subjects were concurrently performing a memory task (encoding and retrieval of visually presented word pairs) and an auditory tone-discrimination task. The PET data were analyzed using multivariate Partial Least Squares (PLS), and the results revealed three sets of neural correlates related to specific task contrasts. Brain activity, relatively greater under conditions of full attention (FA) than DA, was identified in the occipital-temporal, medial, and ventral-frontal areas, whereas areas showing relatively more activity under DA than FA were found in the cerebellum, temporo-parietal, left anterior-cingulate gyrus, and bilateral dorsolateral-prefrontal areas. Regions more active during encoding than during retrieval were located in the hippocampus, temporal and the prefrontal cortex of the left hemisphere, and regions more active during retrieval than during encoding included areas in the medial and right-prefrontal cortex, basal ganglia, thalamus, and cuneus. DA at encoding was associated with specific decreases in rCBF in the left-prefrontal areas, whereas DA at retrieval was associated with decreased rCBF in a relatively small region in the right-prefrontal cortex. These different patterns of activity are related to the behavioral results, which showed a substantial decrease in memory performance when the DA task was performed at encoding, but no change in memory levels when the DA task was performed at retrieval.
引用
收藏
页码:267 / 280
页数:14
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