Elevated β-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

被引：621

作者：

Yang, LB

Lindholm, K

Yan, RQ

Citron, M

Xia, WM

Yang, XL

Beach, T

Sue, L

Wong, P

Price, D

Li, R

Shen, Y ^{[1
]}

机构：

[1] Sun Hlth Res Inst, Haldeman Lab Mol & Cellular Neurobiol, Sun City, AZ USA

[2] Sun Hlth Res Inst, Brain Bank & Civin Neuropathol Lab, Sun City, AZ USA

[3] Sun Hlth Res Inst, LJ Roberts Ctr Alzheimers Res, Sun City, AZ USA

[4] Pharmacia Corp, Dept Cell & Mol Biol, Kalamazoo, MI USA

[5] Amgen Inc, Dept Neurosci, Thousand Oaks, CA 91320 USA

[6] Harvard Univ, Brigham & Womens Hosp, Sch Med, Ctr Neurol Dis, Boston, MA 02115 USA

[7] Johns Hopkins Univ, Sch Med, Dept Pathol, Neuropathol Lab, Baltimore, MD 21205 USA

来源：

NATURE MEDICINE | 2003年 / 9卷 / 01期

关键词：

D O I：

10.1038/nm0103-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：3 / 4

页数：2

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