A new stilbene glucoside from the roots of Polygonum multiflorum Thunb.

被引:62
作者
Xu, Ming-Lu
Zheng, Ming Shan
Lee, Yeon-Kyong
Moon, Dong-Cheol
Lee, Chong-Soon
Woo, Mi-Hee
Jeong, Byeong-Seon
Lee, Eung Seok
Jahng, Yurngdong
Chang, Hyeun-Wook
Lee, Seung-Ho
Son, Jong-Keun [1 ]
机构
[1] Yeungnam Univ, Coll Pharm, Kyongsan 712749, South Korea
[2] Chungbuk Natl Univ, Coll Pharm, Cheongju 361763, South Korea
[3] Yeungnam Univ, Coll Nat Sci, Dept Biochem, Kyongsan 712749, South Korea
[4] Catholic Univ Daegu, Coll Pharm, Gyongsan 712702, South Korea
关键词
Polygonum multiflorum; NMR; stilbene glucoside;
D O I
10.1007/BF02969276
中图分类号
R914 [药物化学];
学科分类号
100701 [药物化学];
摘要
One new stilbene glucoside (6), along with five known compounds (1-5), were isolated from the roots of Polygonum multiflorum Thumb., and their chemical structures established based on physicochemical and spectroscopic data. Of the compounds, compound 3 showed DNA topoisomerase I and II inhibitory activities.
引用
收藏
页码:946 / 951
页数:6
相关论文
共 18 条
[1]
[Anonymous], KOR J PHARMACOG
[2]
Chandra Shekhar M., 1981, Vac News, V12, P12
[3]
2,2-diphenyl-1-picrylhydrazyl radical-scavenging active components from Polygonum multiflorum Thunb. [J].
Chen, Y ;
Wang, MF ;
Rosen, RT ;
Ho, CT .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1999, 47 (06) :2226-2228
[4]
Acylated flavonol glycosides from leaves of Planchonia grandis [J].
Crublet, ML ;
Long, C ;
Sévenet, T ;
Hadi, HA ;
Lavaud, C .
PHYTOCHEMISTRY, 2003, 64 (02) :589-594
[5]
DELOURDES M, 1981, PHYTOCHEMISTRY, V20, P1947
[6]
Do JC, 1988, KOR J PHARMACOGN, V19, P170
[7]
Fukuda M, 1996, CANCER RES, V56, P789
[8]
Antitumor and antiinflammatory constituents from Celtis sinensis [J].
Kim, DK ;
Lim, JP ;
Kim, JW ;
Park, HW ;
Eun, JS .
ARCHIVES OF PHARMACAL RESEARCH, 2005, 28 (01) :39-43
[9]
STUDIES OF THE CONSTITUENTS OF PURGATIVE CRUDE DRUGS .13. DIMERIC HYDROANTHRACENES FROM THE UNRIPE SEEDS OF CASSIA-TOROSA [J].
KITANAKA, S ;
TAKIDO, M .
PHYTOCHEMISTRY, 1982, 21 (08) :2103-2106
[10]
Lignans from the bark of Machilus thunbergii and their DNA topoisomerases I and II inhibition and cytotoxicity [J].
Li, G ;
Lee, CS ;
Woo, MH ;
Lee, SH ;
Chang, HW ;
Son, JK .
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2004, 27 (07) :1147-1150