Surveillance of methicillin-resistant Staphylococcus aureus (MRSA) and Enterobacteriaceae producing extended-spectrum β-lactamase (ESBLE) in Northern France:: a five-year multicentre incidence study

被引：63

作者：

Albertini, MT ^{[1
]}

Astagneau, P ^{[1
]}

Benoit, C ^{[1
]}

Berardi, L ^{[1
]}

Berrouane, Y ^{[1
]}

Boisivon, A ^{[1
]}

Cahen, P ^{[1
]}

Cattoen, C ^{[1
]}

Costa, Y ^{[1
]}

Darchis, P ^{[1
]}

Delière, E ^{[1
]}

Demontrond, D ^{[1
]}

Eb, F ^{[1
]}

Golliot, F ^{[1
]}

Grise, G ^{[1
]}

Harel, A ^{[1
]}

Koeck, JL ^{[1
]}

Lepennec, MP ^{[1
]}

Malbrunot, C ^{[1
]}

Marcollin, M ^{[1
]}

Maugat, S ^{[1
]}

Nouvellon, M ^{[1
]}

Pangon, B ^{[1
]}

Ricouart, S ^{[1
]}

Roussel-Delvallez, M ^{[1
]}

Vachée, A ^{[1
]}

Carbonne, A ^{[1
]}

Marty, L ^{[1
]}

Jarlier, V ^{[1
]}

机构：

[1] C CLIN Nord, Inst Cordeliers, F-75006 Paris, France

来源：

JOURNAL OF HOSPITAL INFECTION | 2002年 / 52卷 / 02期

关键词：

antibiotic resistance; epidemiology; prevention; surveillance; nosocomial;

D O I：

10.1053/jhin.2002.1286

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

In order to measure the incidence of methicillin-resistant Staphylococcus aureus (MRSA) and of Enterobacteriaceae producing extended-spectrum beta-lactamase (ESBLE), and to evaluate the impact of the national guidelines for multidrug-resistant bacteria (MDRB) prevention in hospitals of Northern France, a multicentre survey was conducted for three months every year starting in 1996, in volunteer hospital laboratories. All clinical specimens positive for MRSA and ESBLE were prospectively surveyed. During the five-year surveillance period, the overall proportion of MRSA was 38.4% in the 28 534 strains of S. aureus, and that of ESBLE was 11.4% in the 6121 strains of Klebsiella pneumoniae and 47.7% in the 2353 strains of Enterobacter aerogenes. The overall incidence rates of clinical specimens positive for MRSA, ESBL-K. pneumoniae and E. aerogenes were 0.84, 0.05 and 0.12/1000 hospital-days (HD), respectively. In the 23 hospitals that participated in the survey every year, the proportion and incidence of MRSA increased from 35.6 to 41.0% and from 0.71 to 0.96/1000 HD (P < 0.001). Conversely, the incidence of ESBLE decreased. Hence, despite recommendations as for isolation precautions, MRSA remains poorly controlled and requires more effective measures. (C) 2002 The Hospital Infection Society.

引用

页码：107 / 113

页数：7

共 35 条

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