Depth electrodes in clinical neurophysiology: neuronal activity and human cognitive function

Depth intracranial electrodes are used in medicine for the diagnosis and treatment of certain medically intractable disorders including epilepsy and parkinsonism. Electrophysiological studies including the recording of neuronal activity via depth electrodes during cognitive tasks allow the mapping of the functional significance of various brain regions for certain cognitive functions. Knowledge accumulated throughout the last several decades allows us to draw some theoretical inferences about neuronal mechanisms of human cognition. The present paper provides a selective review of studies of neuronal activity of the human brain in relation to language, verbal memory and error detection. (C) 2000 Elsevier Science B.V. All rights reserved.