The host-tumor immune conflict: from immunosuppression to resistance and destruction

被引：325

作者：

Chouaib, S ^{[1
]}

AsselinPaturel, C ^{[1
]}

MamiChouaib, F ^{[1
]}

Caignard, A ^{[1
]}

Blay, JY ^{[1
]}

机构：

[1] CTR LEON BERARD,CYTOKINES & CANC UNIT,F-69008 LYON,FRANCE

来源：

IMMUNOLOGY TODAY | 1997年 / 18卷 / 10期

关键词：

D O I：

10.1016/S0167-5699(97)01115-8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A successful immune response against a tumor is dependent on the cytokine repertoire present at the tumor site. Salem Chouaib and colleagues discuss evidence that, to escape the immune system, tumor cells not only produce immunosuppressive cytokines but also employ strategies involving altered susceptibility to tumor necrosis factor and Fas cytotoxic pathways and, in some circumstances, use of the Fas ligand to neutralize effector cells.

引用

页码：493 / 497

页数：5

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