Structural biology - Pumping ions

被引：49

作者：

MacLennan, DH

Green, NM

机构：

[1] Univ Toronto, Banting & Best Dept Med Res, Toronto, ON M5G 1L6, Canada

[2] Natl Inst Med Res, London NW7 1AA, England

来源：

NATURE | 2000年 / 405卷 / 6787期

关键词：

D O I：

10.1038/35015206

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

An influx of calcium ions into the cytoplasm activates a variety of cellular processes. The Ca2+ concentration is then returned to sub-micromolar levels by an ATP-driven Ca2+pump. The first high-resolution structure of such a pump reveals in exquisite detail the structural features that may underlie the pump's activity.

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收藏

页码：633 / 634

页数：2

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