2,6-bis[(2S)-tetrahydrofuran-2-yl]phenyl diselenide: An effective reagent for asymmetric electrophilic addition reactions to olefins

被引：57

作者：

Deziel, R

Malenfant, E

Thibault, C

Frechette, S

Gravel, M

机构：

[1] Bio-Méga Research Division, Boehringer Ingelheim (Canada) Ltd., Lavai, Que. H7S 2G5

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 27期

关键词：

D O I：

10.1016/S0040-4039(97)01030-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The enantioselective synthesis of a new and extremely effective organoselenium reagent (2) is reported. This chiral reagent was found to react with alkenes with a very high degree of facial selectivity in selenomethoxylation and ring closure reactions. In some cases the diastereoselectivities were found to be as high as 98%. (C) 1997 Elsevier Science Ltd.

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页码：4753 / 4756

页数：4

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