In-process ATR-FTIR spectroscopy for closed-loop supersaturation control of a batch crystallizer producing monosodium glutamate crystals of defined size

被引：116

作者：

Grön, H

Borissova, A

Roberts, KJ ^{[1
]}

机构：

[1] Univ Leeds, Dept Chem Engn, Inst Particle Sci & Engn, Leeds LS2 9JT, W Yorkshire, England

[2] Heriot Watt Univ, Res Sch Phys Sci & Engn, Ctr Mol & Interface Engn, Edinburgh EH14 4AS, Midlothian, Scotland

来源：

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH | 2003年 / 42卷 / 01期

关键词：

D O I：

10.1021/ie020346d

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Closed-loop computer control of solution supersaturation based on in-process measurements of the concentration using ATR-FTIR spectroscopy and adaptive determination of the corresponding temperature profile has been applied to control the crystallization of monosodium glutamate from an aqueous solution. The crystal size and its distribution are varied and optimized by applying different control strategies such as rapid desupersaturation, constant supersaturation, and step-changing supersaturation profiles.

引用

页码：198 / 206

页数：9

共 24 条

[1] On-line analytical techniques for monitoring crystallisation processes of organic speciality chemicals [J].