Olfactory identification in elderly schizophrenia and Alzheimer's disease

被引:53
作者
Moberg, PJ
Doty, RL
Mahr, RN
Mesholam, RI
Arnold, SE
Turetsky, BI
Gur, RE
机构
[1] UNIV PENN,DEPT PSYCHIAT,SCHIZOPHRENIA CTR,PHILADELPHIA,PA 19104
[2] UNIV PENN,DEPT OTORHINOLARYNGOL,SCHIZOPHRENIA CTR,CTR SMELL & TASTE,PHILADELPHIA,PA 19104
关键词
olfaction; smell; identification; elderly; schizophrenia; Alzheimer's;
D O I
10.1016/S0197-4580(97)00015-8
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
In the present study we assessed olfactory identification ability using the University of Pennsylvania Smell Identification Test (UPSIT) in 16 elderly patients with schizophrenia (ES), 20 patients with a diagnosis of probable Alzheimer's disease (AD), and 20 healthy elderly controls (EC). Both patient groups exhibited marked deficits in UPSIT performance relative to controls. ES and AD patients with similar levels of general cognitive impairment did not differ on the UPSIT, suggesting that the two disorders may share a common dysfunction in olfactory brain regions. While there have been recent reports of greater olfactory impairment in males, neither patient group exhibited significant gender differences on the UPSIT. (C) 1997 Elsevier Science Inc.
引用
收藏
页码:163 / 167
页数:5
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