Opioid, cheating on its receptors, exacerbates pain

被引：20

作者：

Altier, Christophe ^{[1
]}

Zamponi, Gerald W. ^{[1
]}

机构：

[1] Univ Calgary, Dept Physiol & Biophys, Hotchkiss Brain Inst, Calgary, AB T2N 1N4, Canada

来源：

NATURE NEUROSCIENCE | 2006年 / 9卷 / 12期

关键词：

D O I：

10.1038/nn1206-1465b

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

Opioids are commonly thought of as compounds that alleviate pain. A new study finds that elevated levels of the opioid dynorphin can unexpectedly activate bradykinin receptors, contributing to the maintenance of neuropathic pain.

引用

页码：1465 / 1467

页数：3

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