The labyrinthine placenta

被引：54

作者：

Rinkenberger, J ^{[1
]}

Werb, Z ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Anat, San Francisco, CA 94143 USA

来源：

NATURE GENETICS | 2000年 / 25卷 / 03期

关键词：

D O I：

10.1038/76985

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Fetal nutrition depends on the placenta, and specifically, the branching of a layer of placental trophoblast cells that sits between the maternal blood and fetal blood vessels. The discovery that expression of the transcription factor Gcm1 in trophoblast stem cells regulates branching of this specialized epithelium offers new insights into a process whose pivotal features have been generally obscure.

引用

页码：248 / 250

页数：3

共 17 条

[1] The glial cells missing-1 protein is essential for branching morphogenesis in the chorioallantoic placenta [J].

Anson-Cartwright, L ;

Dawson, K ;

Holmyard, D ;

Fisher, SJ ;

Lazzarini, RA ;

Cross, JC .

NATURE GENETICS, 2000, 25 (03) :311-314

[2] Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all αv integrins [J].

Bader, BL ;

Rayburn, H ;

Crowley, D ;

Hynes, RO .

CELL, 1998, 95 (04) :507-519

[3] PPARγ is required for placental, cardiac, and adipose tissue development [J].

Barak, Y ;

Nelson, MC ;

Ong, ES ;

Jones, YZ ;

Ruiz-Lozano, P ;

Chien, KR ;

Koder, A ;

Evans, RM .

MOLECULAR CELL, 1999, 4 (04) :585-595

[4] Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta [J].

Giroux, S ;

Tremblay, M ;

Bernard, D ;

Cadrin-Girard, JF ;

Aubry, S ;

Larouche, L ;

Rousseau, S ;

Huot, J ;

Landry, J ;

Jeannotte, L ;

Charron, J .

CURRENT BIOLOGY, 1999, 9 (07) :369-372

[5]

Janatpour MJ, 2000, DEVELOPMENT, V127, P549

[6]

Kingdom JCP, 1999, ADV EXP MED BIOL, V474, P259

[7] Esx1 is an X-chromosome-imprinted regulator of placental development and fetal growth [J].

Li, YH ;

Behringer, RR .

NATURE GENETICS, 1998, 20 (03) :309-311

[8]

Quaggin SE, 1999, DEVELOPMENT, V126, P5771

[9]

Rinkenberger JL, 1997, DEV GENET, V21, P6, DOI 10.1002/(SICI)1520-6408(1997)21:1&lt

[10]

6::AID-DVG2&gt

← 1 2 →