What's in a name? Y chromosomes, surnames and the genetic genealogy revolution

被引:118
作者
King, Turi E. [1 ]
Jobling, Mark A. [1 ]
机构
[1] Univ Leicester, Dept Genet, Leicester LE1 7RH, Leics, England
基金
英国惠康基金;
关键词
POPULATION-DIVERGENCE; MITOCHONDRIAL-DNA; MUTATION-RATES; RESOLUTION; ANCESTRY; IRELAND; MICROSATELLITES; HAPLOGROUPS; PHYLOGENY; PEDIGREES;
D O I
10.1016/j.tig.2009.06.003
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Heritable surnames are highly diverse cultural markers of coancestry in human populations. A patrilineal surname is inherited in the same way as the non-recombining region of the Y chromosome and there should, therefore, be a correlation between the two. Studies of Y haplotypes within surnames, mostly of the British Isles, reveal high levels of coancestry among surname cohorts and the influence of confounding factors, including multiple founders for names, non-paternities and genetic drift. Combining molecular genetics and surname analysis illuminates population structure and history, has potential applications in forensic studies and, in the form of 'genetic genealogy', is an area of rapidly growing interest for the public.
引用
收藏
页码:351 / 360
页数:10
相关论文
共 75 条
[1]   A haplotype map of the human genome [J].
Altshuler, D ;
Brooks, LD ;
Chakravarti, A ;
Collins, FS ;
Daly, MJ ;
Donnelly, P ;
Gibbs, RA ;
Belmont, JW ;
Boudreau, A ;
Leal, SM ;
Hardenbol, P ;
Pasternak, S ;
Wheeler, DA ;
Willis, TD ;
Yu, FL ;
Yang, HM ;
Zeng, CQ ;
Gao, Y ;
Hu, HR ;
Hu, WT ;
Li, CH ;
Lin, W ;
Liu, SQ ;
Pan, H ;
Tang, XL ;
Wang, J ;
Wang, W ;
Yu, J ;
Zhang, B ;
Zhang, QR ;
Zhao, HB ;
Zhao, H ;
Zhou, J ;
Gabriel, SB ;
Barry, R ;
Blumenstiel, B ;
Camargo, A ;
Defelice, M ;
Faggart, M ;
Goyette, M ;
Gupta, S ;
Moore, J ;
Nguyen, H ;
Onofrio, RC ;
Parkin, M ;
Roy, J ;
Stahl, E ;
Winchester, E ;
Ziaugra, L ;
Shen, Y .
NATURE, 2005, 437 (7063) :1299-1320
[2]   How well does paternity confidence match actual paternity? Evidence from worldwide nonpaternity rates [J].
Anderson, Kermyt G. .
CURRENT ANTHROPOLOGY, 2006, 47 (03) :513-520
[3]  
[Anonymous], 2005, NEW SCI
[4]  
ATHEY TW, 2008, J GENET GENEAL, V4, P149
[5]   The brave new era of human genetic testing [J].
Bandelt, Hans-Juergen ;
Yao, Yong-Gang ;
Richards, Martin B. ;
Salas, Antonio .
BIOESSAYS, 2008, 30 (11-12) :1246-1251
[6]   Median-joining networks for inferring intraspecific phylogenies [J].
Bandelt, HJ ;
Forster, P ;
Röhl, A .
MOLECULAR BIOLOGY AND EVOLUTION, 1999, 16 (01) :37-48
[7]   Admixture dynamics in Hispanics: A shift in the nuclear genetic ancestry of a South American population isolate [J].
Bedoya, Gabriel ;
Montoya, Patricia ;
Garcia, Jenny ;
Soto, Ivan ;
Bourgeois, Stephane ;
Carvajal, Luis ;
Labuda, Damian ;
Alvarez, Victor ;
Ospina, Jorge ;
Hedrick, Philip W. ;
Ruiz-Linares, Andres .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (19) :7234-7239
[8]   Excavating past population structures by surname-based sampling: The genetic legacy of the Vikings in northwest England [J].
Bowden, Georgina R. ;
Balaresque, Patricia ;
King, Turi E. ;
Hansen, Ziff ;
Lee, Andrew C. ;
Pergl-Wilson, Giles ;
Hurley, Emma ;
Roberts, Stephen J. ;
Waite, Patrick ;
Jesch, Judith ;
Jones, Abigail L. ;
Thomas, Mark G. ;
Harding, Stephen E. ;
Jobling, Mark A. .
MOLECULAR BIOLOGY AND EVOLUTION, 2008, 25 (02) :301-309
[9]   Celebrity genomes alarm researchers [J].
Check, Erika .
NATURE, 2007, 447 (7143) :358-359
[10]   Use of surname models in human population biology: A review of recent developments [J].
Colantonio, SE ;
Lasker, GW ;
Kaplan, BA ;
Fuster, V .
HUMAN BIOLOGY, 2003, 75 (06) :785-807