Biofilm formation by asymptomatic and virulent urinary tract infectious Escherichia coli strains

被引：64

作者：

Hancock, Viktoria ^{[1
]}

Ferrieres, Lionel ^{[1
]}

Klemm, Per ^{[1
]}

机构：

[1] Tech Univ Denmark, Microbial Adhes Grp, Ctr Biomed Microbiol, Bioctr, DK-2800 Lyngby, Denmark

来源：

FEMS MICROBIOLOGY LETTERS | 2007年 / 267卷 / 01期

关键词：

asymptomatic bacteriuria; biofilm formation; urinary tract infection; UPEC; urine growth;

D O I：

10.1111/j.1574-6968.2006.00507.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Escherichia coli is the most common organism associated with asymptomatic bacteriuria (ABU) in humans. In contrast to uropathogenic E. coli (UPEC) that cause symptomatic urinary tract infection, very little is known about the mechanisms by which these strains colonize the urinary tract. Here, we have investigated the biofilm-forming capacity on abiotic surfaces of groups of ABU strains and UPEC strains in human urine. We found that there is a strong bias; ABU strains were significantly better biofilm formers than UPEC strains. Our data suggest that biofilm formation in urinary tract infectious E. coli seems to be associated with ABU strains and appears to be an important strategy used by these strains for persistence in this high-flow environment.

引用

页码：30 / 37

页数：8

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